Recent advances in modified chitosan-based drug delivery systems for transmucosal applications: A comprehensive review

MHA Elella, OM Kolawole - International Journal of Biological …, 2024 - Elsevier
In recent years, transmucosal drug delivery systems (TDDSs) have been extensively studied
because they protect therapeutic agents from degradation; improve drug residence time at …

[HTML][HTML] Advancements in chitosan-based nanoparticles for pulmonary drug delivery

TM Zacaron, MLS Silva, MP Costa, DM Silva, AC Silva… - Polymers, 2023 - mdpi.com
The evolution of respiratory diseases represents a considerable public health challenge, as
they are among the leading causes of death worldwide. In this sense, in addition to the high …

Enhanced oral delivery of hesperidin-loaded sulfobutylether-β-cyclodextrin/chitosan nanoparticles for augmenting its hypoglycemic activity: in vitro-in vivo assessment …

ME Elmoghayer, NM Saleh, II Abu Hashim - Drug Delivery and …, 2024 - Springer
Hesperidin (Hsd), a bioactive phytomedicine, experienced an antidiabetic activity versus
both Type 1 and Type 2 Diabetes mellitus. However, its intrinsic poor solubility and …

Fabrication of lignocellulose/liquid metal-based conductive eutectic hydrogel composite for strain sensors

D Zhao, L Wang, K Fang, J Luo, X Zhou… - International Journal of …, 2024 - Elsevier
High conductive and freeze-resistant hydrogels with adhesion function are ideal candidates
for soft electronic devices. However, it remains a challenge to design appropriate conductive …

Synthesis of novel bioadhesive hydrogels via facile Thiol-Ene click chemistry for wound healing applications

MM Fares, ZH Jabani, LA Abu-Haniyi - International Journal of Biological …, 2024 - Elsevier
Abstract Development of outstanding, cost-effective and elastic hydrogels as bioadhesive
using Thiol-Ene click chemistry was verified. The visible light photocrosslinkable hydrogels …

Synthesis of novel chitosan/sodium hyaluronate/iridium hydrogel nanocomposite for wound healing application

LJ Chen, TC Yu, BH Huang, KC Tso, YF Song… - International journal of …, 2024 - Elsevier
A novel chitosan/sodium hyaluronate/iridium (CHI/SH/Ir) hydrogel nanocomposite with a
unique microstructure containing vertically aligned pores is fabricated via an electrophoresis …

Synthesis of high-performance antibacterial agent based on incorporated vancomycin into MOF-modified lignin nanocomposites

S Perveen, R Zhai, X Chen, T Kanwal, MR Shah… - International Journal of …, 2024 - Elsevier
The alarming rise in antibiotic resistance necessitates urgent action, particularly against the
backdrop of resistant bacteria evolving to render conventional antibiotics less effective …

Optimized mucoadhesive niosomal carriers for intranasal delivery of carvedilol: A quality by design approach

ZAT Azrak, MS Taha, J Jagal, A Elsherbeny… - International Journal of …, 2024 - Elsevier
Abstract Carvedilol (CV), a β-blocker essential for treating cardiovascular diseases, faces
bioavailability challenges due to poor water solubility and first-pass metabolism. This study …

In vitro and in vivo evaluation of tedizolid nanoparticle incorporated buccal films for oromucosal infections

HE Gültekin, HH Aydın, A Şahiner, FE Soylu… - International Journal of …, 2024 - Elsevier
A novel tedizolid phosphate (TZP) nanoparticle (NP)-loaded buccal film formulation was
developed for the treatment of buccal wounds infected with S. aureus. TZP-loaded chitosan …