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Auger electrons for cancer therapy–a review
Abstract Background Auger electrons (AEs) are very low energy electrons that are emitted
by radionuclides that decay by electron capture (eg 111 In, 67 Ga, 99m Tc, 195m Pt, 125 I …
by radionuclides that decay by electron capture (eg 111 In, 67 Ga, 99m Tc, 195m Pt, 125 I …
Development of radiopharmaceuticals for targeted alpha therapy: Where do we stand?
RM Pallares, RJ Abergel - Frontiers in Medicine, 2022 - frontiersin.org
Targeted alpha therapy is an oncological treatment, where cytotoxic doses of alpha radiation
are locally delivered to tumor cells, while the surrounding healthy tissue is minimally …
are locally delivered to tumor cells, while the surrounding healthy tissue is minimally …
Potent candidates for Targeted Auger Therapy: Production and radiochemical considerations
D Filosofov, E Kurakina, V Radchenko - Nuclear Medicine and Biology, 2021 - Elsevier
Abstract Targeted Auger Therapy represents great potential for the therapy of diseases
which require a high degree of selectivity on the cellular level (eg for therapy of metastatic …
which require a high degree of selectivity on the cellular level (eg for therapy of metastatic …
A guide to 90Y radioembolization and its dosimetry
Radioembolization gains continuous traction as a primarily palliative radiation treatment for
hepatic tumours. A form of nuclear medicine therapy, Yttrium-90 containing microspheres …
hepatic tumours. A form of nuclear medicine therapy, Yttrium-90 containing microspheres …
MIRD pamphlet no. 25: MIRDcell V2. 0 software tool for dosimetric analysis of biologic response of multicellular populations
B Vaziri, H Wu, AP Dhawan, P Du… - Journal of Nuclear …, 2014 - jnm.snmjournals.org
Patients undergoing nuclear medicine procedures for cancer therapy are administered
radiopharmaceuticals that emit various types of radiation. Because radiation has differential …
radiopharmaceuticals that emit various types of radiation. Because radiation has differential …
Computational nuclear oncology toward precision radiopharmaceutical therapies: current tools, techniques, and uncharted territories
Radiopharmaceutical therapy (RPT), with its targeted delivery of cytotoxic ionizing radiation,
demonstrates significant potential for treating a wide spectrum of malignancies, with …
demonstrates significant potential for treating a wide spectrum of malignancies, with …
Internal microdosimetry of alpha-emitting radionuclides
At the tissue level, energy deposition in cells is determined by the microdistribution of alpha-
emitting radionuclides in relation to sensitive target cells. Furthermore, the highly localized …
emitting radionuclides in relation to sensitive target cells. Furthermore, the highly localized …
The presence of iodinated contrast agents amplifies DNA radiation damage in computed tomography
C Pathe, K Eble, D Schmitz‐Beuting… - Contrast media & …, 2011 - Wiley Online Library
The purpose of this study was to determine the influence of iodinated contrast agents on the
formation of DNA double‐strand breaks in vitro in lymphocytes and to verify these results in …
formation of DNA double‐strand breaks in vitro in lymphocytes and to verify these results in …
Cellular dosimetry of 111In using Monte Carlo N-particle computer code: comparison with analytic methods and correlation with in vitro cytotoxicity
Z Cai, JP Pignol, C Chan… - Journal of Nuclear …, 2010 - jnm.snmjournals.org
Our objective was to compare Monte Carlo N-particle (MCNP) self-and cross-doses from
111In to the nucleus of breast cancer cells with doses calculated by reported analytic …
111In to the nucleus of breast cancer cells with doses calculated by reported analytic …
Auger radiopharmaceutical therapy targeting prostate-specific membrane antigen in a micrometastatic model of prostate cancer
Auger radiopharmaceutical therapy is a promising strategy for micrometastatic disease
given high linear energy transfer and short range in tissues, potentially limiting normal tissue …
given high linear energy transfer and short range in tissues, potentially limiting normal tissue …