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[HTML][HTML] Advances in the development of antiviral strategies against parvovirus B19
E Manaresi, G Gallinella - Viruses, 2019 - mdpi.com
Parvovirus B19 (B19V) is a human pathogenic virus, responsible for an ample range of
clinical manifestations. Infections are usually mild, self-limiting, and controlled by the …
clinical manifestations. Infections are usually mild, self-limiting, and controlled by the …
N6-methyladenosine modification of a parvovirus-encoded small noncoding RNA facilitates viral DNA replication through recruiting Y-family DNA polymerases
Human bocavirus 1 (HBoV1) is a human parvovirus that causes lower respiratory tract
infections in young children. It contains a single-stranded (ss) DNA genome of~ 5.5 kb that …
infections in young children. It contains a single-stranded (ss) DNA genome of~ 5.5 kb that …
Genetic basis of myocarditis: myth or reality?
E Arbustini, N Narula, L Giuliani, A Di Toro - … : pathogenesis, diagnosis and …, 2020 - Springer
The genetic basis of myocarditis remains an intriguing concept, at least as long as the
definition of myocarditis constitutes the definitive presence of myocardial inflammation …
definition of myocarditis constitutes the definitive presence of myocardial inflammation …
RNA binding motif protein RBM45 regulates expression of the 11-kilodalton protein of parvovirus B19 through binding to novel intron splicing enhancers
During infection of human parvovirus B19 (B19V), one viral precursor mRNA (pre-mRNA) is
transcribed by a single promoter and is alternatively spliced and alternatively …
transcribed by a single promoter and is alternatively spliced and alternatively …
Cellular cleavage and polyadenylation specificity factor 6 (CPSF6) mediates nuclear import of human bocavirus 1 NP1 protein and modulates viral capsid protein …
X Wang, P Xu, F Cheng, Y Li, Z Wang, S Hao… - Journal of …, 2020 - journals.asm.org
ABSTRACT Human bocavirus 1 (HBoV1), which belongs to the genus Bocaparvovirus of the
Parvoviridae family, causes acute respiratory tract infections in young children. In vitro …
Parvoviridae family, causes acute respiratory tract infections in young children. In vitro …
SYNCRIP facilitates porcine parvovirus viral DNA replication through the alternative splicing of NS1 mRNA to promote NS2 mRNA formation
S Chen, B Miao, N Chen, C Chen, T Shao, X Zhang… - Veterinary …, 2021 - Springer
Porcine Parvovirus (PPV), a pathogen causing porcine reproductive disorders, encodes two
capsid proteins (VP1 and VP2) and three nonstructural proteins (NS1, NS2 and SAT) in …
capsid proteins (VP1 and VP2) and three nonstructural proteins (NS1, NS2 and SAT) in …
High-throughput screening identifies inhibitors for parvovirus B19 infection of human erythroid progenitors
K Ning, A Roy, F Cheng, P Xu, S Kleiboeker… - Journal of …, 2022 - journals.asm.org
ABSTRACT Parvovirus B19 (B19V) infection can cause hematological disorders and fetal
hydrops during pregnancy. Currently, no antivirals or vaccines are available for the …
hydrops during pregnancy. Currently, no antivirals or vaccines are available for the …
Porcine deltacoronavirus nucleocapsid protein interacts with the Grb2 through its proline-rich motifs to induce activation of the Raf-MEK-ERK signal pathway and …
M Li, L Zhang, P Zhou, Z Zhang… - Journal of General …, 2024 - microbiologyresearch.org
Porcine deltacoronavirus (PDCoV), an enteropathogenic coronavirus, causes severe watery
diarrhoea, dehydration and high mortality in piglets, which has the potential for cross …
diarrhoea, dehydration and high mortality in piglets, which has the potential for cross …
[HTML][HTML] Establishment of a parvovirus B19 NS1-expressing recombinant adenoviral vector for killing megakaryocytic leukemia cells
P Xu, X Wang, Y Li, J Qiu - Viruses, 2019 - mdpi.com
Adenoviral viral vectors have been widely used for gene-based therapeutics, but commonly
used serotype 5 shows poor transduction efficiency into hematopoietic cells. In this study, we …
used serotype 5 shows poor transduction efficiency into hematopoietic cells. In this study, we …
GATA1 transcription factor targets the gene expression of B19 virus in HEK293 cell line
Methods: HEK293 cells were transfected with pHI0 plasmid containing the B19V genome
and the plasmid of the GATA1 genome. The quantity of B19V mRNAs (NS1, 7.5 kDa, and 11 …
and the plasmid of the GATA1 genome. The quantity of B19V mRNAs (NS1, 7.5 kDa, and 11 …