Effect of agents affecting bone homeostasis on short‐and long‐term implant failure

J Jung, JI Ryu, GJ Shim… - Clinical oral implants …, 2023 - Wiley Online Library
Objectives To review the current evidence on the relationship between agents that affect
bone homeostasis and dental implant failures. Materials and Methods Electronic searches …

Bone-on-a-chip platforms and integrated biosensors: Towards advanced in vitro bone models with real-time biosensing

Y Zhang, T Yu, J Ding, Z Li - Biosensors and Bioelectronics, 2023 - Elsevier
Bone diseases, such as osteoporosis and bone defects, often lead to structural and
functional deformities of the patient's body. Understanding the complicated pathophysiology …

[HTML][HTML] Osteogenesis and osteoclastogenesis on a chip: Engineering a self-assembling 3D coculture

MAM Vis, F Zhao, ESR Bodelier, CM Bood, J Bulsink… - Bone, 2023 - Elsevier
Healthy bone is maintained by the process of bone remodeling. An unbalance in this
process can lead to pathologies such as osteoporosis which are often studied with animal …

Impacts of bisphosphonates on the bone and its surrounding tissues: mechanistic insights into medication-related osteonecrosis of the jaw

B Srivichit, C Thonusin, N Chattipakorn… - Archives of …, 2022 - Springer
Bisphosphonates are widely used as anti-resorptive agents for the treatment of various bone
and joint diseases, including advanced osteoporosis, multiple myeloma, bone metastatic …

Biomechanical analysis of alveolar bones with compromised quality supporting a 4-unit implant bridge; a possible association with implant-related sequestration (IRS)

Y Yoon, I Kang, G Noh, YD Kwon - Clinical Oral Investigations, 2024 - Springer
Objectives This study aimed to investigate the strain in the bone surrounding dental implants
supporting a 4-unit bridge and assess the role of excessive strain as a possible risk factor for …

Advances in the Construction and Application of Bone‐on‐a‐Chip Based on Microfluidic Technologies

C Zhong, Z Tang, X Yu, L Wang, C Ren… - … Research Part B …, 2024 - Wiley Online Library
ABSTRACT Bone‐on‐a‐chip (BOC) models that based on microfluidic technology have
widely applied to understand bone physiology and the pathogenesis of related diseases. In …

Mechanical stimuli-mediated modulation of bone cell function—implications for bone remodeling and angiogenesis

W Liang, X Wu, Y Dong, X Chen, P Zhou, F Xu - Cell and Tissue Research, 2021 - Springer
Bone remodeling, expressed as bone formation and turnover, is a complex and dynamic
process closely related to its form and function. Different events, such as development …

Quantification of cell contractile behavior based on non-destructive macroscopic measurement of tension forces on bioprinted hydrogel

S Pragnere, N El Kholti, L Gudimard, L Essayan… - Journal of the …, 2022 - Elsevier
Contraction assay based on surface measurement have been widely used to evaluate cell
contractility in 3D models. This method is straightforward and requires no specific …

A vascularized bone-on-a-chip model development via exploring mechanical stimulation for evaluation of fracture healing therapeutics

B Das, SV Seesala, P Pal, T Roy, PG Roy, S Dhara - In vitro models, 2022 - Springer
Bone is the major connective tissue maintaining the structural integrity of the human body.
However, fracture and many skeletal degenerative diseases can compromise this function …

In vitro bioprinted 3D model enhancing osteoblast-to-osteocyte differentiation

S Pragnere, L Essayan, N El-Kholti, E Petiot… - …, 2024 - iopscience.iop.org
In vitro bone models are pivotal for understanding tissue behavior and cellular responses,
particularly in unravelling certain pathologies' mechanisms and assessing the impact of new …