Myeloid cells in the central nervous system (CNS) represent a heterogeneous class of
innate immune cells that contribute to the maintenance of tissue homeostasis differentially …

Macrophages are ubiquitous cells that reside in all major tissues. Counter to long-held
beliefs, we now know that resident macrophages in many organs are seeded during …

Microglia are critical nervous system-specific cells influencing brain development,
maintenance of the neural environment, response to injury, and repair. They contribute to …

Microglia, the resident innate immune cells in the brain, have long been implicated in the
pathology of neurodegenerative diseases. Accumulating evidence points to activated …

This paper summarizes pathological changes that affect microglial cells in the human brain
during aging and in aging-related neurodegenerative diseases, primarily Alzheimer's …

Functional recovery from peripheral nerve injury and repair depends on a multitude of
factors, both intrinsic and extrinsic to neurons. Neuronal survival after axotomy is a …

Damage to the central nervous system (CNS) elicits the activation of both astrocytes and
microglia. This review is focused on the principal features that characterize the activation of …

Microglia form a regularly spaced network of resident glial cells throughout the central
nervous system (CNS). They are morphologically, immunophenotypically and functionally …

We have studied microglial morphology in the human cerebral cortex of two nondemented
subjects using high‐resolution LN‐3 immunohistochemistry. Several abnormalities in …

There is increasing confusion about the meaning of the terms inflammation,
neuroinflammation, and microglial inflammation. We aim in this review to achieve greater …