With heart and cardiovascular diseases continually challenging healthcare systems
worldwide, translating basic research on cardiac (patho) physiology into clinical care is …

Integrative models of cardiac physiology are important for understanding disease and
planning intervention. Multimodal cardiovascular imaging plays an important role in defining …

The majority of patients with clinically diagnosed heart failure have normal systolic pump
function and are commonly categorized as suffering from diastolic heart failure. The left …

Personalized biophysical modeling of the heart is a useful approach for noninvasively
analyzing and predicting in vivo cardiac mechanics. Three main developments support this …

Quantitative measurement of the material properties (eg, stiffness) of biological tissues is
poised to become a powerful diagnostic tool. There are currently several methods in the …

Cardiac mechanics models are developed to represent a high level of detail, including
refined anatomies, accurate cell mechanics models, and platforms to link microscale …

The role of myocardial contractile force in the progression of cardiovascular diseases such
as heart failure (HF) has been the focus of many studies. In order to better understand the …

Impaired systolic ventricular function is common in patients diagnosed with heart failure (HF)
or ischaemic heart disease. The diminished contractile performance with impaired …

Background Heart failure (HF) is defined as the inability of the heart to meet the body's
requirements for blood flow as a result of impaired function of one or both ventricles (see …

Les données cliniques disponibles pour le diagnostic et la planification de thérapies sont de
plus en plus variées et complexes, ce qui apporte des informations plus riches, mais rend la …