Sex differences in frailty: a systematic review and meta-analysis

EH Gordon, NM Peel, M Samanta, O Theou… - Experimental …, 2017 - Elsevier
Background It is a well-described clinical phenomenon that females live longer than males,
yet tend to experience greater levels of co-morbidity and disability. Females can therefore be …

Human age reversal: Fact or fiction?

AA Johnson, BW English, MN Shokhirev… - Aging …, 2022 - Wiley Online Library
Although chronological age correlates with various age‐related diseases and conditions, it
does not adequately reflect an individual's functional capacity, well‐being, or mortality risk …

The Asia-Pacific clinical practice guidelines for the management of frailty

E Dent, C Lien, WS Lim, WC Wong, CH Wong… - Journal of the American …, 2017 - Elsevier
Abstract Objective To develop Clinical Practice Guidelines for the screening, assessment
and management of the geriatric condition of frailty. Methods An adapted Grading of …

Gut microbial features and circulating metabolomic signatures of frailty in older adults

Y Pu, Z Sun, H Zhang, Q Huang, Z Wang, Z Mei… - Nature Aging, 2024 - nature.com
Frailty, a multidimensional indicator of suboptimal aging, reflects cumulative declines across
multiple physiological systems. Although age-related changes have been reported in gut …

How old is my dog? Identification of rational age grou**s in pet dogs based upon normative age-linked processes

ND Harvey - Frontiers in veterinary science, 2021 - frontiersin.org
Behavioral development is a lifelong process where cognitive traits such as learning and
memory may be expected to take quadratic or linear trajectories. It is common practice for …

Association of frailty with survival: a systematic literature review

T Shamliyan, KMC Talley, R Ramakrishnan… - Ageing research …, 2013 - Elsevier
Frailty is a known risk factor for those aged 65 and over, and its prevalence increases with
age. Definitions of frailty vary widely, and prevalence estimates are affected by the way frailty …

Measures of frailty in population-based studies: an overview

K Bouillon, M Kivimaki, M Hamer, S Sabia, EI Fransson… - BMC geriatrics, 2013 - Springer
Background Although research productivity in the field of frailty has risen exponentially in
recent years, there remains a lack of consensus regarding the measurement of this …

Defining 'elderly'in clinical practice guidelines for pharmacotherapy

S Singh, B Bajorek - Pharmacy practice, 2014 - pmc.ncbi.nlm.nih.gov
Objective: To identify how 'elderly'patients are defined and considered within Australian
clinical guidelines for the use of pharmacotherapy. Method: Guidelines pertaining to the use …

A standard procedure for creating a frailty index

SD Searle, A Mitnitski, EA Gahbauer, TM Gill… - BMC geriatrics, 2008 - Springer
Background Frailty can be measured in relation to the accumulation of deficits using a frailty
index. A frailty index can be developed from most ageing databases. Our objective is to …

Prevalence and 10‐year outcomes of frailty in older adults in relation to deficit accumulation

X Song, A Mitnitski, K Rockwood - Journal of the American …, 2010 - Wiley Online Library
OBJECTIVES: To evaluate the prevalence and 10‐year outcomes of frailty in older adults in
relation to deficit accumulation. DESIGN: Prospective cohort study. SETTING: The National …