5-Ene-4-thiazolidinones–An efficient tool in medicinal chemistry

D Kaminskyy, A Kryshchyshyn, R Lesyk - European journal of medicinal …, 2017 - Elsevier
The presented review is an attempt to summarize a huge volume of data on 5-ene-4-
thiazolidinones being a widely studied class of small molecules used in modern organic and …

[PDF][PDF] Review on (azo, formazane, sulfazane)-compounds

NM Aljamali - International Journal of Innovations in Scientific …, 2019 - ijise.in
Azo compounds represent the essential compound of organic reactions and the basic
material for preparing many ligands, complexes, dyes, polymers, antioxidants, bioactive …

5-Arylidenethioxothiazolidinones as inhibitors of tyrosyl–DNA phosphodiesterase I

VR Sirivolu, SKV Vernekar, C Marchand… - Journal of medicinal …, 2012 - ACS Publications
Tyrosyl–DNA phosphodiesterase I (Tdp1) is a cellular enzyme that repairs the irreversible
topoisomerase I (Top1)–DNA complexes and confers chemotherapeutic resistance to Top1 …

Synthesis of fused thiopyrano [2, 3-d][1, 3] thiazoles via hetero-Diels–Alder reaction related tandem and domino processes

N Zelisko, D Atamanyuk, Y Ostapiuk, A Bryhas… - Tetrahedron, 2015 - Elsevier
Abstract Various novel rel-(5R, 5aR, 11bS)-2, 6-dioxo-3, 5a, 6, 11b-tetrahydro-2Н, 5H-
chromeno [4′, 3′: 4, 5] thiopyrano [2, 3-d][1, 3] thiazole-5-carboxylic acid derivatives were …

Thiopyrano[2,3-d]Thiazoles as New Efficient Scaffolds in Medicinal Chemistry

A Kryshchyshyn, O Roman, A Lozynskyi… - Scientia Pharmaceutica, 2018 - mdpi.com
This review presents the up to date development of fused thiopyranothiazoles that comprise
one of the thiazolidine derivatives classes. Thiazolidine and thiazolidinone-related …

Synthesis and anticancer activity of some new thiopyrano [2, 3-d] thiazoles incorporating pyrazole moiety

NH Metwally, MA Badawy, DS Okpy - Chemical and Pharmaceutical …, 2015 - jstage.jst.go.jp
The knöevenagel condensation of 3-phenyl-4-thioxo-2-thiazolidinone (1) with 1-phenyl-3-
aryl-1H-pyrazole-4-carbaldehydes 2a–d in refluxing glacial acetic acid or in polyethylene …

A new domino-Knoevenagel–hetero-Diels–Alder reaction

VS Matiychuk, RB Lesyk, MD Obushak, A Gzella… - Tetrahedron …, 2008 - Elsevier
Various novel 3, 5a, 6, 11b-tetrahydro-2H, 5H-chromeno [4′, 3′: 4, 5] thiopyrano [2, 3-d][1,
3] thiazol-2-ones were synthesized in 60–80% yields via domino-Knoevenagel–hetero-Diels …

Synthesis and anticancer activity of novel thiopyrano[2,3-d]thiazole-based compounds containing norbornane moiety

D Atamanyuk, B Zimenkovsky… - Journal of Sulfur …, 2008 - Taylor & Francis
The series of 9, 14-disubstituted 3, 7-dithia-5, 14-diazapentacyclo [9.5. 1.02, 10.04, 8.012,
16] heptadecen-4 (8)-triones-6, 13, 15 were synthesized using hetero-Diels-Alder reactions …

Crotonic, cynnamic, and propiolic acids motifs in the synthesis of thiopyrano [2, 3-d][1, 3] thiazoles via hetero-Diels–Alder reaction and related tandem processes

N Zelisko, D Atamanyuk, O Vasylenko, A Bryhas… - Tetrahedron, 2014 - Elsevier
Abstract Various novel thiopyrano [2, 3-d][1, 3] thiazol-2-one-6-carboxylic acids derivatives
were synthesized in 54–86% yields via hetero-Diels–Alder reactions and related acylation …

Synthesis and structure elucidation of thiopyrano [2, 3-d] thiazole-6-carbonitriles as adducts of Michael reaction

A Lozynskyi, I Yushyn, Y Shepeta, O Karpenko… - Journal of Molecular …, 2022 - Elsevier
Abstract A series of thiopyrano [2, 3-d] thiazole derivatives via Michael reaction of
malononitrile and 5-arylideneisorhodanine were synthesized. The further acid or alkaline …