The ecology and evolutionary dynamics of meiotic drive

AK Lindholm, KA Dyer, RC Firman, L Fishman… - Trends in ecology & …, 2016 - cell.com
Meiotic drivers are genetic variants that selfishly manipulate the production of gametes to
increase their own rate of transmission, often to the detriment of the rest of the genome and …

Meiotic drive mechanisms: lessons from Drosophila

C Courret, CH Chang, KHC Wei… - … of the Royal …, 2019 - royalsocietypublishing.org
Meiotic drivers are selfish genetic elements that bias their transmission into gametes, often
to the detriment of the rest of the genome. The resulting intragenomic conflicts triggered by …

Resistance to natural and synthetic gene drive systems

TAR Price, N Windbichler, RL Unckless… - Journal of …, 2020 - academic.oup.com
Scientists are rapidly develo** synthetic gene drive elements intended for release into
natural populations. These are intended to control or eradicate disease vectors and pests, or …

New perspectives on the causes and consequences of male meiotic drive

C Courret, X Wei, AM Larracuente - Current Opinion in Genetics & …, 2023 - Elsevier
Gametogenesis is vulnerable to selfish genetic elements that bias their transmission to the
next generation by cheating meiosis. These so-called meiotic drivers are widespread in …

Selfing is the safest sex for Caenorhabditis tropicalis

LM Noble, J Yuen, L Stevens, N Moya, R Persaud… - Elife, 2021 - elifesciences.org
Mating systems have profound effects on genetic diversity and compatibility. The convergent
evolution of self-fertilization in three Caenorhabditis species provides a powerful lens to …

Functional Significance of Satellite DNAs: Insights From Drosophila

AS Shatskikh, AA Kotov, VE Adashev… - Frontiers in cell and …, 2020 - frontiersin.org
Since their discovery more than 60 years ago, satellite repeats are still one of the most
enigmatic parts of eukaryotic genomes. Being non-coding DNA, satellites were earlier …

Epistatic selection on a selfish Segregation Distorter supergene–drive, recombination, and genetic load

B Navarro-Dominguez, CH Chang, CL Brand… - Elife, 2022 - elifesciences.org
Meiotic drive supergenes are complexes of alleles at linked loci that together subvert
Mendelian segregation resulting in preferential transmission. In males, the most common …

A Pooled Sequencing Approach Identifies a Candidate Meiotic Driver in Drosophila

KHC Wei, HM Reddy, C Rathnam, J Lee, D Lin, S Ji… - Genetics, 2017 - academic.oup.com
Mendel's Law of equal segregation states that each of the two alleles in a diploid organism
has an equal probability of being transmitted into... Meiotic drive occurs when a selfish …

Convergent evolution of complex genomic rearrangements in two fungal meiotic drive elements

J Svedberg, S Hosseini, J Chen, AA Vogan… - Nature …, 2018 - nature.com
Meiotic drive is widespread in nature. The conflict it generates is expected to be an important
motor for evolutionary change and innovation. In this study, we investigated the genomic …

Balancing Selection Drives the Maintenance of Genetic Variation in Drosophila Antimicrobial Peptides

JR Chapman, T Hill, RL Unckless - Genome biology and …, 2019 - academic.oup.com
Genes involved in immune defense against pathogens provide some of the most well-known
examples of both directional and balancing selection. Antimicrobial peptides (AMPs) are …