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Obsessive-compulsive disorder: puzzles and prospects
Obsessive-compulsive disorder is a severe and disabling psychiatric disorder that presents
several challenges for neuroscience. Recent advances in its genetic and developmental …
several challenges for neuroscience. Recent advances in its genetic and developmental …
Beyond dichotomies in reinforcement learning
Reinforcement learning (RL) is a framework of particular importance to psychology,
neuroscience and machine learning. Interactions between these fields, as promoted through …
neuroscience and machine learning. Interactions between these fields, as promoted through …
Adaptive learning under expected and unexpected uncertainty
A Soltani, A Izquierdo - Nature Reviews Neuroscience, 2019 - nature.com
The outcome of a decision is often uncertain, and outcomes can vary over repeated
decisions. Whether decision outcomes should substantially affect behaviour and learning …
decisions. Whether decision outcomes should substantially affect behaviour and learning …
Improving the reliability of computational analyses: Model-based planning and its relationship with compulsivity
Background Computational models show great promise in map** latent decision-making
processes onto dissociable neural substrates and clinical phenotypes. One prominent …
processes onto dissociable neural substrates and clinical phenotypes. One prominent …
A mechanistic staging model of reward processing alterations in individuals with binge‐type eating disorders
Altered reward processing is thought to characterize binge‐type eating disorders, but the
exact nature of these alterations is unclear. A more fine‐grained understanding of whether …
exact nature of these alterations is unclear. A more fine‐grained understanding of whether …
Improving the reliability of model-based decision-making estimates in the two-stage decision task with reaction-times and drift-diffusion modeling
A well-established notion in cognitive neuroscience proposes that multiple brain systems
contribute to choice behaviour. These include:(1) a model-free system that uses values …
contribute to choice behaviour. These include:(1) a model-free system that uses values …
Closing the loop in psychiatric deep brain stimulation: physiology, psychometrics, and plasticity
AS Widge - Neuropsychopharmacology, 2024 - nature.com
Deep brain stimulation (DBS) is an invasive approach to precise modulation of
psychiatrically relevant circuits. Although it has impressive results in open-label psychiatric …
psychiatrically relevant circuits. Although it has impressive results in open-label psychiatric …
Meta-analyses of the functional neural alterations in subjects with Internet gaming disorder: Similarities and differences across different paradigms
Internet gaming disorder (IGD) has become a global public health concern due to its
increasing prevalence and potential negative consequences. Researchers have sought to …
increasing prevalence and potential negative consequences. Researchers have sought to …
Computational models of drug use and addiction: A review.
In this brief review, we describe current computational models of drug-use and addiction that
fall into 2 broad categories: mathematically based models that rely on computational …
fall into 2 broad categories: mathematically based models that rely on computational …
Current limits of experimental research into habits and future directions
Highlights•Insensitivity to devaluation could be due to habits or weak goal-directed
control.•Limited direct evidence for habits as a function of behavioral repetition in …
control.•Limited direct evidence for habits as a function of behavioral repetition in …