Understanding the extracellular vesicle surface for clinical molecular biology

S Hallal, Á Tűzesi, GE Grau… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) are lipid‐membrane enclosed nanoparticles that play significant
roles in health and disease. EVs are abundant in body fluids and carry an array of molecules …

Harnessing extracellular vesicle heterogeneity for diagnostic and therapeutic applications

RP Carney, RR Mizenko, BT Bozkurt, N Lowe… - Nature …, 2024 - nature.com
Extracellular vesicles (EVs) are diverse nanoparticles with large heterogeneity in size and
molecular composition. Although this heterogeneity provides high diagnostic value for liquid …

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

Emerging methods in biomarker identification for extracellular vesicle‐based liquid biopsy

Y Liang, BM Lehrich, S Zheng… - Journal of Extracellular …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are released by many cell types and distributed within various
biofluids. EVs have a lipid membrane‐confined structure that allows for carrying unique …

[HTML][HTML] Glycosylation in extracellular vesicles: Isolation, characterization, composition, analysis and clinical applications

V Vrablova, N Kosutova, A Blsakova, A Bertokova… - Biotechnology …, 2023 - Elsevier
This review provides a comprehensive overview of our understanding of the role that
glycans play in the formation, loading and release of extracellular vesicles (EVs). The …

Nanoalgosomes: Introducing extracellular vesicles produced by microalgae

G Adamo, D Fierli, DP Romancino… - Journal of …, 2021 - Wiley Online Library
Cellular, inter‐organismal and cross kingdom communication via extracellular vesicles
(EVs) is intensively studied in basic science with high expectation for a large variety of bio …

Defined MSC exosome with high yield and purity to improve regenerative activity

JY Kim, WK Rhim, YI Yoo, DS Kim… - Journal of Tissue …, 2021 - journals.sagepub.com
Exosomes derived from mesenchymal stem cells (MSCs) have been studied as vital
components of regenerative medicine. Typically, various isolation methods of exosomes …

Understanding extracellular vesicle and nanoparticle heterogeneity: Novel methods and considerations

W Phillips, E Willms, AF Hill - Proteomics, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are a heterogeneous population of membrane‐enclosed
nanoparticles released by cells. They play a role in intercellular communication and are …

Bolstering the secretion and bioactivities of umbilical cord MSC-derived extracellular vesicles with 3D culture and priming in chemically defined media

JY Kim, WK Rhim, SG Cha, J Woo, JY Lee, CG Park… - Nano …, 2022 - Springer
Human mesenchymal stem cells (hMSCs)-derived extracellular vesicles (EVs) have been
known to possess the features of the origin cell with nano size and have shown therapeutic …

MicroRNA-34a-5p expression in the plasma and in its extracellular vesicle fractions in subjects with Parkinson's disease: An exploratory study

I Grossi, A Radeghieri, L Paolini… - International …, 2021 - spandidos-publications.com
Parkinson's disease (PD) is an important disabling age-related disorder and is the second
most common neuro-degenerative disease. Currently, no established molecular biomarkers …