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NAMPT and NAPRT: two metabolic enzymes with key roles in inflammation
Nicotinamide phosphoribosyltransferase (NAMPT) and nicotinate
phosphoribosyltransferase (NAPRT) are two intracellular enzymes that catalyze the first step …
phosphoribosyltransferase (NAPRT) are two intracellular enzymes that catalyze the first step …
Metabolic regulation of histone post-translational modifications
Histone post-translational modifications regulate transcription and other DNA-templated
functions. This process is dynamically regulated by specific modifying enzymes whose …
functions. This process is dynamically regulated by specific modifying enzymes whose …
The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants
The inclusion of familial myeloid malignancies as a separate disease entity in the revised
WHO classification has renewed efforts to improve the recognition and management of this …
WHO classification has renewed efforts to improve the recognition and management of this …
Analysis of cancer-related lncRNAs using gene ontology and KEGG pathways
Background Cancer is a disease that involves abnormal cell growth and can invade or
metastasize to other tissues. It is known that several factors are related to its initiation …
metastasize to other tissues. It is known that several factors are related to its initiation …
Beyond energy metabolism: exploiting the additional roles of NAMPT for cancer therapy
CM Heske - Frontiers in oncology, 2020 - frontiersin.org
Tumor cells have increased requirements for NAD+. Thus, many cancers exhibit an
increased reliance on NAD+ production pathways. This dependence may be exploited …
increased reliance on NAD+ production pathways. This dependence may be exploited …
The role of adipokines in breast cancer: current evidence and perspectives
Purpose The current review shows evidence for the role of adipokines in breast cancer (BC)
pathogenesis summarizing the mechanisms underlying the association between adipokines …
pathogenesis summarizing the mechanisms underlying the association between adipokines …
Classic and novel adipocytokines at the intersection of obesity and cancer: diagnostic and therapeutic strategies
Abstract Purpose of Review In this review, we investigate the role of classic and novel
adipocytokines in cancer pathogenesis synopsizing the mechanisms underlying the …
adipocytokines in cancer pathogenesis synopsizing the mechanisms underlying the …
The role of extracellular and intracellular Nicotinamide phosphoribosyl-transferase in cancer: Diagnostic and therapeutic perspectives and challenges
Nicotinamide phosphoribosyl-transferase (Nampt) or pre-B cell colony-enhancing factor or
visfatin represents a pleiotropic molecule acting as an enzyme, a cytokine and a growth …
visfatin represents a pleiotropic molecule acting as an enzyme, a cytokine and a growth …
[HTML][HTML] Impact of ERG3 mutations and expression of ergosterol genes controlled by UPC2 and NDT80 in Candida parapsilosis azole resistance
J Branco, M Ola, RM Silva, E Fonseca… - Clinical Microbiology …, 2017 - Elsevier
Objectives Candida parapsilosis is a healthcare-related fungal pathogen particularly
common among immunocompromised patients. Our understanding of antifungal resistance …
common among immunocompromised patients. Our understanding of antifungal resistance …
Altered epigenetic profiles in the placenta of preeclamptic and intrauterine growth restriction patients
C Norton, D Clarke, J Holmstrom, I Stirland… - Cells, 2023 - mdpi.com
Intrauterine growth restriction (IUGR) and preeclampsia (PE) are placental pathologies
known to complicate pregnancy and cause neonatal disorders. To date, there is a limited …
known to complicate pregnancy and cause neonatal disorders. To date, there is a limited …