Phyllanthus emblica Linn, a prominent member of the euphorbiaceae family, exhibits
extensive distribution across a multitude of tropical and subtropical nations. Referred to as …

Flavonoids are a large subgroup of polyphenols known to be sourced from over 6000
natural products, including fruits, vegetables, bark, and herbs. Due to their antioxidant …

Computational pharmacology and chemistry of drug-like properties along with
pharmacokinetic studies have made it more amenable to decide or predict a potential drug …

In the present work, two novel complexes of zinc (II) and copper (II) were synthesized from
the ligand 2-((2-hydroxyethyl) amino) quinoline-3-carbaldehyde (H 2 L) in a 1: 2 metal-to …

Poor pharmacokinetic and safety profiles create significant hurdles in the drug development
process. This work focuses on a detailed understanding of drug discovery interplay among …

Computer modeling is a method that is widely used in scientific investigations to predict the
biological activity, toxicity, pharmacokinetics, and synthesis strategy of compounds based on …

Abstract The FT-IR and FT-Raman spectra was recorded within the range of 4000-500 cm−
1 and compared with the theoretically obtained spectra. The 13 C and 1 H NMR chemical …

Introduction Oxidative stress plays an essential role in the pathogenesis of chronic diseases.
Disrupting the Keap1-Nrf2 pathway by binding Keap1 is identified as a potential strategy to …

Cyclin-dependent kinase inhibition is considered a promising target for cancer treatment for
its crucial role in cell cycle regulation. Pyrazolo pyrimidine derivatives were well established …

Isoxazole belongs to the class of five-membered heterocyclic compounds. The process of
develo** new drugs has significantly gained attention due to inadequate pharmacokinetic …