Hemoperfusion adsorbents for removal of common toxins in liver and kidney failure: recent progress, challenges, and prospects
S Wu, P Yue, Y Ma, Y Zou, W Liang, Q Ye - Advanced Materials, 2023 - Wiley Online Library
Liver and kidney failure can lead to extensive accumulation of toxic metabolites in the blood
and tissues, such as bilirubin, blood ammonia, endotoxins, cytokines, creatinine, uric acid …
and tissues, such as bilirubin, blood ammonia, endotoxins, cytokines, creatinine, uric acid …
Physically stimulus-responsive nanoparticles for therapy and diagnosis
Nanoparticles offer numerous advantages in various fields of science, particularly in
medicine. Over recent years, the use of nanoparticles in disease diagnosis and treatments …
medicine. Over recent years, the use of nanoparticles in disease diagnosis and treatments …
Glucosamine-modified mesoporous silica-coated magnetic nanoparticles: a “Raisin-Cake”-like structure as an efficient theranostic platform for targeted methotrexate …
This study presents the synthesis of glucosamine-modified mesoporous silica-coated
magnetic nanoparticles (MNPs) as a therapeutic platform for the delivery of an anticancer …
magnetic nanoparticles (MNPs) as a therapeutic platform for the delivery of an anticancer …
Mesoporous silica nanostructure modified with azo gatekeepers for colon targeted delivery of 5‐fluorouracil
In this study, amino‐functionalized mesoporous silica (MS) particles were synthesized and
loaded with the anticancer drug, 5‐Fu. In a post‐modification reaction, the pores were gated …
loaded with the anticancer drug, 5‐Fu. In a post‐modification reaction, the pores were gated …
An orally deliverable ornithine-based self-assembling polymer nanomedicine ameliorates hyperammonemia in acetaminophen-induced acute liver injury
Abstract l-Ornithine (Orn) is a core amino acid responsible for ammonia detoxification in the
body via the hepatic urea cycle. Clinical studies in Orn therapy have focused on …
body via the hepatic urea cycle. Clinical studies in Orn therapy have focused on …
Low‐dose ketamine improves animals' locomotor activity and decreases brain oxidative stress and inflammation in ammonia‐induced neurotoxicity
Abstract Ammonium ion (NH4+) is the major suspected molecule responsible for
neurological complications of hepatic encephalopathy (HE). No specific pharmacological …
neurological complications of hepatic encephalopathy (HE). No specific pharmacological …
Ashwagandha-loaded nanocapsules improved the behavioral alterations, and blocked MAPK and induced Nrf2 signaling pathways in a hepatic encephalopathy rat …
Ashwagandha (ASH), a vital herb in Ayurvedic medicine, demonstrated potent preclinical
hepato-and neuroprotective effects. However, its efficacy is limited due to low oral …
hepato-and neuroprotective effects. However, its efficacy is limited due to low oral …
Mesoporous silica application as an antidote of methotrexate and evaluation of the long-term oral administration: In vitro and in vivo study
Amino-functionalized mesoporous silica (MS-NH2) was synthesized, characterized, and
applied as an adsorbent and antidote agent of methotrexate (MTX) in vitro and in vivo …
applied as an adsorbent and antidote agent of methotrexate (MTX) in vitro and in vivo …
[HTML][HTML] Engineered Mesoporous Silica-Based Nanoparticles: Characterization of Surface Properties
A Grisolia, M De Santo, M Curcio, PA Cavallaro… - Materials, 2024 - mdpi.com
Mesoporous silica-based nanomaterials have emerged as multifunctional platforms with
applications spanning catalysis, medicine, and nanotechnology. Since their synthesis in the …
applications spanning catalysis, medicine, and nanotechnology. Since their synthesis in the …
Carnitine in alleviation of complications caused by Acute Valproic Acid toxicity; an Exprimental Study on mice
Introduction: Hyperammonemia and hepatotoxicity are well-known complications of valproic
acid (VPA) poisoning. The objective of this study is to evaluate the potential role of carnitine …
acid (VPA) poisoning. The objective of this study is to evaluate the potential role of carnitine …