Interactions between morphological plaque characteristics and coronary physiology: from pathophysiological basis to clinical implications

S Yang, BK Koo, J Narula - Cardiovascular Imaging, 2022 - jacc.org
High-risk coronary plaque refers to a distinct set of plaque characteristics prone to future
coronary events. Coronary physiology represents a group of indexes reflective of the local …

A review study on blood in human coronary artery: Numerical approach

R Pandey, M Kumar, J Majdoubi, M Rahimi-Gorji… - Computer methods and …, 2020 - Elsevier
Computational fluid dynamics (CFD) study of blood flow in human coronary artery is one of
the emerging fields of Biomed-ical engineering. In present review paper, Finite Volume …

Identification of high-risk plaques destined to cause acute coronary syndrome using coronary computed tomographic angiography and computational fluid dynamics

JM Lee, G Choi, BK Koo, D Hwang, J Park… - Cardiovascular …, 2019 - jacc.org
Objectives The authors investigated the utility of noninvasive hemodynamic assessment in
the identification of high-risk plaques that caused subsequent acute coronary syndrome …

Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow

AC Vion, M Kheloufi, A Hammoutene, J Poisson… - Proceedings of the …, 2017 - pnas.org
It has been known for some time that atherosclerotic lesions preferentially develop in areas
exposed to low SS and are characterized by a proinflammatory, apoptotic, and senescent …

High coronary shear stress in patients with coronary artery disease predicts myocardial infarction

A Kumar, EW Thompson, A Lefieux, DS Molony… - Journal of the American …, 2018 - jacc.org
Background: Coronary lesions with low fractional flow reserve (FFR) that are treated
medically are associated with higher revascularization rates. High wall shear stress (WSS) …

Role of low endothelial shear stress and plaque characteristics in the prediction of nonculprit major adverse cardiac events: the PROSPECT study

PH Stone, A Maehara, AU Coskun, CC Maynard… - JACC: Cardiovascular …, 2018 - jacc.org
Objectives: This study sought to determine whether low endothelial shear stress (ESS) adds
independent prognostication for future major adverse cardiac events (MACE) in coronary …

Effect of wall elasticity on hemodynamics and wall shear stress in patient-specific simulations in the coronary arteries

P Eslami, J Tran, Z **, J Karady… - Journal of …, 2020 - asmedigitalcollection.asme.org
Wall shear stress (WSS) has been shown to be associated with myocardial infarction (MI)
and progression of atherosclerosis. Wall elasticity is an important feature of hemodynamic …

Invasive FFR and noninvasive CFR in the evaluation of ischemia: what is the future?

NP Johnson, KL Gould, MF Di Carli… - Journal of the American …, 2016 - jacc.org
This review provides an integrative and forward-looking perspective on the gamut of
coronary physiology for the diagnosis and management of atherosclerosis. Because clinical …

Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques

Z He, J Luo, M Lv, Q Li, W Ke, X Niu, Z Zhang - Frontiers in Neurology, 2023 - frontiersin.org
Atherosclerosis is an important cause of cerebrovascular and cardiovascular disease (CVD).
Lipid infiltration, inflammation, and altered vascular stress are the critical mechanisms that …

Characteristics of wall shear stress and pressure of intracranial atherosclerosis analyzed by a computational fluid dynamics model: a pilot study

Z Chen, H Qin, J Liu, B Wu, Z Cheng, Y Jiang… - Frontiers in …, 2020 - frontiersin.org
Background: Although wall shear stress (WSS) and pressure play important roles in plaque
vulnerability, characteristics of the two indices in intracranial atherosclerosis (ICAS) have not …