Necrosis: a specific form of programmed cell death?

SY Proskuryakov, AG Konoplyannikov… - Experimental cell research, 2003 - Elsevier
For a long time necrosis was considered as an alternative to programmed cell death,
apoptosis. Indeed, necrosis has distinct morphological features and it is accompanied by …

Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA

M Eldh, K Ekström, H Valadi, M Sjöstrand, B Olsson… - PloS one, 2010 - journals.plos.org
Background Exosomes are small extracellular nanovesicles of endocytic origin that mediate
different signals between cells, by surface interactions and by shuttling functional RNA from …

Morphological criteria to distinguish cell death induced by apoptotic and necrotic treatments

S Rello, JC Stockert, VL Moreno, A Gamez, M Pacheco… - Apoptosis, 2005 - Springer
We present a comparative study of apoptotic and necrotic morphology (light and scanning
electron microscopy), induced by well known experimental conditions (photodynamic …

Hydrogen peroxide induces apoptosis-like death in Leishmania donovani promastigotes

M Das, SB Mukherjee, C Shaha - Journal of Cell Science, 2001 - journals.biologists.com
Leishmania donovani promastigotes introduced into the bloodstream by sandfly vectors, are
exposed to reactive oxygen species like H2O2 during phagocytosis by the host …

Hydrogen sulfide protects MC3T3-E1 osteoblastic cells against H2O2-induced oxidative damage—implications for the treatment of osteoporosis

ZS Xu, XY Wang, DM **ao, LF Hu, M Lu, ZY Wu… - Free Radical Biology …, 2011 - Elsevier
Osteoporosis is a bone disease that leads to an increased risk of fracture. Oxidative damage
is an important contributor to the morphological and functional changes in the development …

Creatine supplementation affords cytoprotection in oxidatively injured cultured mammalian cells via direct antioxidant activity

P Sestili, C Martinelli, G Bravi, G Piccoli, R Curci… - Free Radical Biology …, 2006 - Elsevier
A growing body of evidence suggests that creatine (Cr) might exert protective effects in a
variety of pathologies where oxidative stress plays a concausal etiologic role; furthermore, it …

Mechanisms of tumor cell necrosis

SY Proskuryakov, VL Gabai - Current pharmaceutical design, 2010 - ingentaconnect.com
Until recently, necrosis, unlike apoptosis, was considered as passive and unregulated form
of cell death. However, during the last decade a number of experimental data demonstrated …

The lncRNA H19-derived MicroRNA-675 promotes liver necroptosis by targeting FADD

R Harari-Steinfeld, M Gefen, A Simerzin… - Cancers, 2021 - mdpi.com
Simple Summary Liver cancer develops mostly in a chronically inflamed liver. The
inflammation process can enhance or suppress the development of liver cancer. H19 is a …

Role of glutathione S-transferases in oxidative stress–induced male germ cell apoptosis

AVSK Rao, C Shaha - Free Radical Biology and Medicine, 2000 - Elsevier
Cellular apoptosis in a tissue may occur for the maintenance of proper ratio of cells or
because of toxic effects of free radicals or other agents. Male germ cell apoptosis is pivotal in …

Anti-NeuGcGM3 antibodies, actively elicited by idiotypic vaccination in nonsmall cell lung cancer patients, induce tumor cell death by an oncosis-like mechanism

AM Hernández, N Rodríguez, JE González… - The Journal of …, 2011 - journals.aai.org
Abstract 1E10 is a murine anti-idiotypic mAb specific for an idiotypic mAb that reacts with
NeuGc-containing gangliosides, sulfatides, and Ags expressed in some human tumors. In …