Quality assurance procedures for mass spectrometry untargeted metabolomics. a review

D Dudzik, C Barbas-Bernardos, A García… - … of pharmaceutical and …, 2018‏ - Elsevier
Untargeted metabolomics, as a global approach, has already proven its great potential and
capabilities for the investigation of health and disease, as well as the wide applicability for …

Transcriptomic and metabolomic data integration

R Cavill, D Jennen, J Kleinjans… - Briefings in …, 2016‏ - academic.oup.com
Many studies now produce parallel data sets from different omics technologies; however, the
task of interpreting the acquired data in an integrated fashion is not trivial. This review covers …

Multi-omics approaches for revealing the complexity of cardiovascular disease

S Doran, M Arif, S Lam, A Bayraktar… - Briefings in …, 2021‏ - academic.oup.com
The development and progression of cardiovascular disease (CVD) can mainly be attributed
to the narrowing of blood vessels caused by atherosclerosis and thrombosis, which induces …

[HTML][HTML] Approaches to integrating metabolomics and multi-omics data: a primer

T Jendoubi - Metabolites, 2021‏ - mdpi.com
Metabolomics deals with multiple and complex chemical reactions within living organisms
and how these are influenced by external or internal perturbations. It lies at the heart of …

Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research

A Scalbert, L Brennan, O Fiehn, T Hankemeier… - Metabolomics, 2009‏ - Springer
Mass spectrometry (MS) techniques, because of their sensitivity and selectivity, have
become methods of choice to characterize the human metabolome and MS-based …

Cytokines and atherosclerosis: a comprehensive review of studies in mice

R Kleemann, S Zadelaar, T Kooistra - Cardiovascular research, 2008‏ - academic.oup.com
In the past few years, inflammation has emerged as a major driving force of atherosclerotic
lesion development. It is now well-established that from early lesion to vulnerable plaque …

Interactions between inflammation and lipid metabolism: relevance for efficacy of anti-inflammatory drugs in the treatment of atherosclerosis

JA van Diepen, JFP Berbée, LM Havekes… - Atherosclerosis, 2013‏ - Elsevier
Dyslipidemia and inflammation are well known causal risk factors the development of
atherosclerosis. The interplay between lipid metabolism and inflammation at multiple levels …

Anti-inflammatory, anti-proliferative and anti-atherosclerotic effects of quercetin in human in vitro and in vivo models

R Kleemann, L Verschuren, M Morrison, S Zadelaar… - Atherosclerosis, 2011‏ - Elsevier
OBJECTIVE: Polyphenols such as quercetin may exert several beneficial effects, including
those resulting from anti-inflammatory activities, but their impact on cardiovascular health is …

Disturbances in cholesterol homeostasis and non-alcoholic fatty liver diseases

P Malhotra, RK Gill, S Saksena, WA Alrefai - Frontiers in Medicine, 2020‏ - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is a major health problem associated with obesity
and other features of the metabolic syndrome including insulin resistance and dyslipidemia …

Metabolomics as a tool for cardiac research

JL Griffin, H Atherton, J Shockcor, L Atzori - Nature Reviews Cardiology, 2011‏ - nature.com
Metabolomics represents a paradigm shift in metabolic research, away from approaches that
focus on a limited number of enzymatic reactions or single pathways, to approaches that …