The past few years have brought substantial progress toward understanding how human
cytomegalovirus (HCMV) enters the remarkably wide spectrum of cell types and tissues that …

The coordinated activities of innate and adaptive immunity are critical for effective protection
against viruses. To counter this, some viruses have evolved sophisticated strategies to …

A systematic quantitative analysis of temporal changes in host and viral proteins throughout
the course of a productive infection could provide dynamic insights into virus-host …

Human cytomegalovirus (HCMV) is a ubiquitous double-stranded DNA virus belonging to
the β-subgroup of the herpesvirus family. After the initial infection, the virus establishes …

Human cytomegalovirus is a widespread pathogen of major medical importance. It causes
significant morbidity and mortality in immunocompromised individuals, and congenital …

Human cytomegalovirus (HCMV) encodes four viral Fc-gamma receptors (vFcγRs) that
counteract antibody-mediated activation in vitro, but their role in infection and pathogenesis …

Human cytomegalovirus (HCMV) is a paradigm of pathogen immune evasion and sustains
lifelong persistent infection in the face of exceptionally powerful host immune responses …

Human cytomegalovirus (HCMV), a ubiquitous beta-herpesvirus, is able to establish lifelong
latency after initial infection. Periodical reactivation occurs after immunosuppression …

Herpesvirus infections are a leading cause of neurodevelopmental delay in newborns and
end-organ disease in immunocompromised patients. One leading strategy to reduce the …

BACKGROUND Most humans have been infected with cytomegalovirus (CMV) by midlife
without clinical signs of disease. However, in settings in which the immune system is …