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Matrix metalloproteinase-9 (MMP-9) and its inhibitors in cancer: A minireview
Matrix metalloproteinases (MMPs) are zinc dependent proteolytic metalloenzyme. MMP-9 is
one of the most complex forms of matrix metalloproteinases. MMP-9 has the ability to …
one of the most complex forms of matrix metalloproteinases. MMP-9 has the ability to …
Biochemical and biological attributes of matrix metalloproteinases
N Cui, M Hu, RA Khalil - Progress in molecular biology and translational …, 2017 - Elsevier
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that are
involved in the degradation of various proteins in the extracellular matrix (ECM). Typically …
involved in the degradation of various proteins in the extracellular matrix (ECM). Typically …
Biological activity of berberine—a summary update
A Och, R Podgórski, R Nowak - Toxins, 2020 - mdpi.com
Berberine is a plant metabolite belonging to the group of isoquinoline alkaloids with strong
biological and pharmacological activity. Currently, berberine is receiving considerable …
biological and pharmacological activity. Currently, berberine is receiving considerable …
[HTML][HTML] Tumor angiogenesis: MMP-mediated induction of intravasation-and metastasis-sustaining neovasculature
EI Deryugina, JP Quigley - Matrix Biology, 2015 - Elsevier
Metastasis is a distinct stage of cancer progression that requires the development of
angiogenic blood vessels serving as conduits for tumor cell dissemination. An accumulated …
angiogenic blood vessels serving as conduits for tumor cell dissemination. An accumulated …
[HTML][HTML] Matrix metalloproteinases in liver injury, repair and fibrosis
The liver is a large highly vascularized organ with a central function in metabolic
homeostasis, detoxification, and immunity. Due to its roles, the liver is frequently exposed to …
homeostasis, detoxification, and immunity. Due to its roles, the liver is frequently exposed to …
Physiology and pathophysiology of matrix metalloproteases
Matrix metalloproteases (MMPs) comprise a family of enzymes that cleave protein substrates
based on a conserved mechanism involving activation of an active site-bound water …
based on a conserved mechanism involving activation of an active site-bound water …
[HTML][HTML] Novel matrix metalloproteinase-9 (MMP-9) inhibitors in cancer treatment
ZA Rashid, SK Bardaweel - International journal of molecular sciences, 2023 - mdpi.com
Matrix metalloproteinases (MMPs) belong to a family of zinc-dependent proteolytic
metalloenzymes. MMP-9, a member of the gelatinase B family, is characterized as one of the …
metalloenzymes. MMP-9, a member of the gelatinase B family, is characterized as one of the …
Matrix metalloproteinases and tumor metastasis
EI Deryugina, JP Quigley - Cancer and metastasis reviews, 2006 - Springer
Functions of individual matrix metalloproteinases (MMPs) differentially expressed by tumor
cells and stromal cells, are finely regulated by their spatial as well as temporal interactions …
cells and stromal cells, are finely regulated by their spatial as well as temporal interactions …
New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: outside-in signaling and relationship to tumor progression
B Bauvois - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2012 - Elsevier
This review focuses on matrix metalloproteinases (MMPs)-2 (gelatinase A) and-9
(gelatinase B), both of which are cancer-associated, secreted, zinc-dependent …
(gelatinase B), both of which are cancer-associated, secreted, zinc-dependent …
Inhibitors of gelatinases (MMP-2 and MMP-9) for the management of hematological malignancies
Abstract Matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) are
collectively known as gelatinases whereas MMP-2 is gelatinase-A and MMP-9 is termed as …
collectively known as gelatinases whereas MMP-2 is gelatinase-A and MMP-9 is termed as …