The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye
disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears …

In the field of predictive, preventive and personalised medicine, researchers are keen to
identify novel and reliable ways to predict and diagnose disease, as well as to monitor …

Context: Thyroid-associated ophthalmopathy (TAO) is the component of Graves' disease
characterized by orbital inflammation and connective tissue remodeling. The IGF-1 receptor …

Purpose: This review represents the current in vitro, in vivo animal and human researches
on the roles of IL-6 in inflammatory ocular disorders. Data sources were literature reviewed …

Thyroid-associated ophthalmoapthy (TAO) is the most common orbital disease. As an
autoimmune disorder, it is caused by self-reactive lymphocytes that escape immune …

Graves' orbitopathy (GO), also known as thyroid-associated ophthalmopathy, is the most
common ocular abnormality of Graves' disease. It is a disfiguring, invalidating, and …

Discovery of robust, selective and specific biomarkers are important for early diagnosis and
monitor progression of human diseases. Eye being a common target for several human …

Considering absence of invasiveness and side effects, tears emerge as a particularly
attractive fluid for biomarker discovery and therefore for daily clinical use. However, to date …

Exosomes contain proteins, lipids, RNA, and DNA that mediate intercellular signaling.
Exosomes can contribute to the pathological processes of various diseases, although their …

Purpose.: To explore changes in lacrimal gland and tear inflammatory cytokines in thyroid-
associated ophthalmopathy (TAO) patients. Methods.: Patients with TAO were divided into …