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Entry and exit of extracellular vesicles to and from the blood circulation
Extracellular vesicles (EVs) are biological nanoparticles that promote intercellular
communication by delivering bioactive cargo over short and long distances. Short-distance …
communication by delivering bioactive cargo over short and long distances. Short-distance …
Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis
Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …
Immunogenicity of extracellular vesicles
Extracellular vesicles (EVs) are promising next‐generation therapeutics and drug delivery
systems due to demonstrated safety and efficacy in preclinical models and early‐stage …
systems due to demonstrated safety and efficacy in preclinical models and early‐stage …
Clinical translation of extracellular vesicles
Extracellular vesicles (EVs) occur in a variety of bodily fluids and have gained recent
attraction as natural materials due to their bioactive surfaces, internal cargo, and role in …
attraction as natural materials due to their bioactive surfaces, internal cargo, and role in …
[HTML][HTML] Mesenchymal stem cell-derived exosomes as drug delivery vehicles in disease therapy
W Zhao, K Li, L Li, R Wang, Y Lei, H Yang… - International Journal of …, 2024 - mdpi.com
Exosomes are small vesicles containing proteins, nucleic acids, and biological lipids, which
are responsible for intercellular communication. Studies have shown that exosomes can be …
are responsible for intercellular communication. Studies have shown that exosomes can be …
[HTML][HTML] Glycosylation in extracellular vesicles: Isolation, characterization, composition, analysis and clinical applications
V Vrablova, N Kosutova, A Blsakova, A Bertokova… - Biotechnology …, 2023 - Elsevier
This review provides a comprehensive overview of our understanding of the role that
glycans play in the formation, loading and release of extracellular vesicles (EVs). The …
glycans play in the formation, loading and release of extracellular vesicles (EVs). The …
Extracellular vesicle and lipoprotein interactions
Extracellular vesicles and lipoproteins are lipid-based biological nanoparticles that play
important roles in (patho) physiology. Recent evidence suggests that extracellular vesicles …
important roles in (patho) physiology. Recent evidence suggests that extracellular vesicles …
Vasculature organotropism in drug delivery
Over the past decades, there has been an exponential increase in the development of
preclinical and clinical nanodelivery systems, and recently, an accelerating demand to …
preclinical and clinical nanodelivery systems, and recently, an accelerating demand to …
Hyaluronic acid: An overlooked extracellular vesicle contaminant
The variable presence of contaminants in extracellular vesicle (EV) samples is one of the
major contributors to a lack of inter‐study reproducibility in the field. Well‐known …
major contributors to a lack of inter‐study reproducibility in the field. Well‐known …
Bioactive sphingolipids as emerging targets for signal transduction in cancer development
W Jia, J Yuan, J Zhang, S Li, W Lin, B Cheng - Biochimica et Biophysica …, 2024 - Elsevier
Sphingolipids, crucial components of cellular membranes, play a vital role in maintaining
cellular structure and signaling integrity. Disruptions in sphingolipid metabolism are …
cellular structure and signaling integrity. Disruptions in sphingolipid metabolism are …