Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy

A Vezzani, S Balosso, T Ravizza - Nature Reviews Neurology, 2019 - nature.com
Epilepsy is a chronic neurological disease characterized by an enduring propensity for
generation of seizures. The pathogenic processes of seizure generation and recurrence are …

A Guide to the Metabolic Pathways and Function of Metabolites Observed in Human Brain 1H Magnetic Resonance Spectra

CD Rae - Neurochemical research, 2014 - Springer
The current knowledge of the normal biochemistry of compounds that give rise to
resonances in human brain proton magnetic resonance spectra measureable at readily …

Serum metabolome associated with severity of acute traumatic brain injury

I Thomas, AM Dickens, JP Posti, E Czeiter… - Nature …, 2022 - nature.com
Complex metabolic disruption is a crucial aspect of the pathophysiology of traumatic brain
injury (TBI). Associations between this and systemic metabolism and their potential …

Imaging evidence and recommendations for traumatic brain injury: conventional neuroimaging techniques

M Wintermark, PC Sanelli, Y Anzai, AJ Tsiouris… - Journal of the American …, 2015 - Elsevier
Imaging plays an essential role in identifying intracranial injury in patients with traumatic
brain injury (TBI). The goals of imaging include (1) detecting injuries that may require …

Imaging evaluation of acute traumatic brain injury

CA Mutch, JF Talbott, A Gean - Neurosurgery Clinics, 2016 - neurosurgery.theclinics.com
In the United States, traumatic brain injury (TBI) is estimated to affect 1.7 million people
annually, leading to approximately 52,000 deaths and 275,000 hospitalizations. TBI plays a …

The biological significance and clinical utility of emerging blood biomarkers for traumatic brain injury

ME Huibregtse, JJ Bazarian, SR Shultz… - … & Biobehavioral Reviews, 2021 - Elsevier
Abstract HUIBREGTSE, ME, Bazarian, JJ, Shultz, SR, and Kawata K. The biological
significance and clinical utility of emerging blood biomarkers for traumatic brain injury …

Magnetic resonance spectroscopy of traumatic brain injury and subconcussive hits: a systematic review and meta–analysis

JM Joyce, PL La, R Walker, AD Harris - Journal of Neurotrauma, 2022 - liebertpub.com
Magnetic resonance spectroscopy (MRS) is a non-invasive technique used to study
metabolites in the brain. MRS findings in traumatic brain injury (TBI) and subconcussive hit …

Altered neurochemistry in former professional soccer players without a history of concussion

IK Koerte, AP Lin, M Muehlmann… - Journal of …, 2015 - liebertpub.com
Soccer is played by more than 250 million people worldwide. Repeatedly heading the ball
may place soccer players at high risk for repetitive subconcussive head impacts (RSHI). This …

Dynamics of choline-containing phospholipids in traumatic brain injury and associated comorbidities

S Javaid, T Farooq, Z Rehman, A Afzal… - International Journal of …, 2021 - mdpi.com
The incidences of traumatic brain injuries (TBIs) are increasing globally because of
expanding population and increased dependencies on motorized vehicles and machines …

Pediatric traumatic brain injury: not just little adults

CC Giza, RB Mink, A Madikians - Current opinion in critical care, 2007 - journals.lww.com
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