Aberrant patterns of brain functional connectivity in the default mode network (DMN) have
been observed across different classes of substance use disorder (SUD) and are associated …

Background Childhood maltreatment is the most important preventable cause of
psychopathology accounting for about 45% of the population attributable risk for childhood …

Uncertainty about a possible future threat disrupts our ability to avoid it or to mitigate its
negative impact and thus results in anxiety. Here, we focus the broad literature on the …

The uncinate fasciculus is a bidirectional, long-range white matter tract that connects lateral
orbitofrontal cortex and Brodmann area 10 with the anterior temporal lobes. Although …

The dynamic interactions between the amygdala and the medial prefrontal cortex (mPFC)
are usefully conceptualized as a circuit that both allows us to react automatically to …

Social anxiety disorder (SAD) is one of the most frequent anxiety disorders. The landmark
meta-analysis of functional neuroimaging studies by Etkin and Wager (2007) revealed …

Despite intensive scientific investigation and public health imperatives, drug addiction
treatment outcomes have not significantly improved in more than 50years. Non-invasive …

Hemispheric asymmetries within the brain have been identified across taxa and have been
extensively studied since the early 19th century. Here, we discuss lateralization of a brain …

Social anxiety disorder patients suffer from excessive anxious responses in social
interaction leading to avoidance behavior and social impairment. Although the amygdala …

At the group-level, deep brain stimulation leads to significant therapeutic benefit in a
multitude of neurological and neuropsychiatric disorders. At the single-patient level …