Biosynthesis and function of 7-deazaguanine derivatives in bacteria and phages

V de Crécy-Lagard, G Hutinet… - Microbiology and …, 2024 - journals.asm.org
Deazaguanine modifications play multifaceted roles in the molecular biology of DNA and
tRNA, sha** diverse yet essential biological processes, including the nuanced fine-tuning …

Interactions of the maternal microbiome with diet, stress, and infection influence fetal development

CH Puglisi, M Kim, M Aldhafeeri… - The FEBS …, 2025 - Wiley Online Library
Humans and other animals contain multitudes of microorganisms including bacteria, fungi,
and viruses, which make up a diverse microbiome. Across body sites including skin …

Sha** microbiota during the first 1000 days of life

A Samarra, E Flores, M Bernabeu… - Probiotics and Child …, 2024 - Springer
Given that the host-microbe interaction is shaped by the immune system response, it is
important to understand the key immune system-microbiota relationship during the period …

Atractylenolide-i alleviates hyperglycemia-induced heart developmental malformations through direct and indirect modulation of the STAT3 pathway

M Wang, T Zhang, Y Li, X Chen, Q Zhang, Y Zheng… - Phytomedicine, 2024 - Elsevier
Background Gestational diabetes could elevate the risk of congenital heart defects (CHD) in
infants, and effective preventive and therapeutic medications are currently lacking …

The microbiome as a modulator of neurological health across the maternal-offspring interface

SB Orchanian, EY Hsiao - The Journal of Clinical Investigation, 2025 - jci.org
The maternal microbiome is emerging as an important factor that influences the neurological
health of mothers and their children. Recent studies highlight how microbial communities in …

Development of systemic and mucosal immune responses against gut microbiota in early life and implications for the onset of allergies

AL Pirker, T Vogl - Frontiers in Allergy, 2024 - frontiersin.org
The early microbial colonization of human mucosal surfaces is essential for the development
of the host immune system. Already during pregnancy, the unborn child is prepared for the …

The roles of the gut microbiota, metabolites, and epigenetics in the effects of maternal exercise on offspring metabolism

J Ren, L Zhou, S Li, Q Zhang… - American Journal of …, 2024 - journals.physiology.org
Metabolic diseases, including obesity, dyslipidemia, and type 2 diabetes, have become
severe challenges worldwide. The Developmental Origins of Health and Disease (DOHaD) …

Potential impact of a pregnant woman's microbiota on the development of fetal heart defects: a review of the literature

K Zych-Krekora, O Sylwestrzak, M Krekora… - Biomedicines, 2024 - mdpi.com
Developments in medicine and biology in recent decades have led to a significant increase
in our knowledge of the complex interactions between the microbiota and human health. In …

[HTML][HTML] Maternal Diet during Pregnancy Alters the Metabolites in Relation to Metabolic and Neurodegenerative Diseases in Young Adult Offspring

SM Kim, S Oh, SS Lee, S Park, YM Hur… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Maternal nutrition during the critical period of pregnancy increases the susceptibility of
offspring to the development of diseases later in life. This study aimed to analyze metabolite …

Maternal probiotic exposure enhances CD8 T cell protective neonatal immunity and modulates offspring metabolome to control influenza virus infection

C Valentin, P Brito Rodrigues, M Verce, S Delbauve… - Gut …, 2025 - Taylor & Francis
Maternal gut microbiota composition contributes to the status of the neonatal immune system
and could influence the early life higher susceptibility to viral respiratory infections. Using a …