Escherichia coli as a host for metabolic engineering
Over the past century, Escherichia coli has become one of the best studied organisms on
earth. Features such as genetic tractability, favorable growth conditions, well characterized …
earth. Features such as genetic tractability, favorable growth conditions, well characterized …
Biosynthetic pathway and metabolic engineering of succinic acid
Succinic acid, a dicarboxylic acid produced as an intermediate of the tricarboxylic acid (TCA)
cycle, is one of the most important platform chemicals for the production of various high …
cycle, is one of the most important platform chemicals for the production of various high …
Reconfiguration of the reductive TCA cycle enables high-level succinic acid production by Yarrowia lipolytica
Z Cui, Y Zhong, Z Sun, Z Jiang, J Deng, Q Wang… - Nature …, 2023 - nature.com
Succinic acid (SA) is an important C4-dicarboxylic acid. Microbial production of SA at low pH
results in low purification costs and hence good overall process economics. However, redox …
results in low purification costs and hence good overall process economics. However, redox …
Designing a periplasmic photosynthetic biohybrid system for succinate and electric energy production
The emergence of photosynthetic biohybrid systems provides an environmentally friendly
and sustainable approach to produce fuels and chemicals in microbial cell factories …
and sustainable approach to produce fuels and chemicals in microbial cell factories …
Anaerobic fermentation of organic solid waste: Recent updates in substrates, products, and the process with multiple products co-production
Y Zhang, X Wang, W Zhu, Y Zhao, N Wang, M Gao… - Environmental …, 2023 - Elsevier
The effective conversion and recycling of organic solid waste contribute to the resolution of
widespread issues such as global environmental pollution, energy scarcity and resource …
widespread issues such as global environmental pollution, energy scarcity and resource …
Progress of succinic acid production from renewable resources: metabolic and fermentative strategies
Succinic acid is a four-carbon dicarboxylic acid, which has attracted much interest due to its
abroad usage as a precursor of many industrially important chemicals in the food …
abroad usage as a precursor of many industrially important chemicals in the food …
Advances in the optimization of central carbon metabolism in metabolic engineering
Z Wu, X Liang, M Li, M Ma, Q Zheng, D Li, T An… - Microbial Cell …, 2023 - Springer
Central carbon metabolism (CCM), including glycolysis, tricarboxylic acid cycle and the
pentose phosphate pathway, is the most fundamental metabolic process in the activities of …
pentose phosphate pathway, is the most fundamental metabolic process in the activities of …
Promising advancement in fermentative succinic acid production by yeast hosts
As a platform chemical with various applications, succinic acid (SA) is currently produced by
petrochemical processing from oil-derived substrates such as maleic acid. In order to …
petrochemical processing from oil-derived substrates such as maleic acid. In order to …
Metabolic engineering of the acid-tolerant yeast Pichia kudriavzevii for efficient L-malic acid production at low pH
Y **, H Xu, T Zhan, Y Qin, F Fan, X Zhang - Metabolic Engineering, 2023 - Elsevier
Currently, the biological production of L-malic acid (L-MA) is mainly based on the
fermentation of filamentous fungi at near-neutral pH, but this process requires large amounts …
fermentation of filamentous fungi at near-neutral pH, but this process requires large amounts …
Cofactor engineering for more efficient production of chemicals and biofuels
M Wang, B Chen, Y Fang, T Tan - Biotechnology advances, 2017 - Elsevier
Cofactors are involved in numerous intracellular reactions and critically influence redox
balance and cellular metabolism. Cofactor engineering can support and promote the …
balance and cellular metabolism. Cofactor engineering can support and promote the …