Oesophageal cancers are prominent worldwide; however, there are few targeted therapies
and survival rates for these cancers remain dismal. Here we performed a comprehensive …

While metabolic reprogramming of cancer cells has long been considered from the
standpoint of how and why cancer cells preferentially utilize glucose via aerobic glycolysis …

The 5-year survival rate in esophageal cancer, although poor, has improved over the past
decade. This review discusses the epidemiologic aspects, pathogenesis, prevention, and …

Esophageal adenocarcinoma (EAC) incidence is increasing while 5-year survival rates
remain less than 15%. A lack of experimental models has hampered progress. We have …

Within the gastrointestinal stem cell niche, nerves help to regulate both normal and
neoplastic stem cell dynamics. Here, we reveal the mechanisms underlying the cancer …

Objective Cigarette smoking is a major risk factor for colorectal cancer (CRC). We aimed to
investigate whether cigarette smoke promotes CRC by altering the gut microbiota and …