Obesity leads to an inflammatory condition that is directly involved in the etiology of
cardiovascular diseases, type 2 diabetes mellitus, and certain types of cancer. The classic …

Nuclear factor-κB (NF-κB) is a transcription factor that plays a crucial role in various
biological processes, including immune response, inflammation, cell growth and survival …

Proliferation is an important part of cancer development and progression. This is manifest by
altered expression and/or activity of cell cycle related proteins. Constitutive activation of …

By virtue of their actions on NF-κB, an inflammatory nuclear transcription factor, various
cytokines have been documented to play important regulatory roles in determining cardiac …

Apicomplexan parasites of the genus Eimeria are organisms which invade the intestinal
tract, causing coccidiosis, an enteric disease of major economic importance worldwide. The …

Transcription factors are pivotal regulators in the cellular life process. Activating transcription
factor 3 (ATF3), a member of the ATF/CREB (cAMP response element-binding protein) …

Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease, including end-
stage kidney disease, and increases the risk of cardiovascular mortality. Although the …

The NF-κB family of transcription factors has an essential role in inflammation and innate
immunity. Furthermore, NF-κB is increasingly recognized as a crucial player in many steps of …

Cellular states are determined by differential expression of the cell's proteins. The
relationship between protein and mRNA expression levels informs about the combined …

The nuclear factor-κB (NF-κB)/REL family of transcription factors has a central role in
coordinating the expression of a wide variety of genes that control immune responses. There …