The matrix in cancer
TR Cox - Nature Reviews Cancer, 2021 - nature.com
The extracellular matrix is a fundamental, core component of all tissues and organs, and is
essential for the existence of multicellular organisms. From the earliest stages of organism …
essential for the existence of multicellular organisms. From the earliest stages of organism …
Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses
LA Costa, N Eiro, M Fraile, LO Gonzalez, J Saá… - Cellular and Molecular …, 2021 - Springer
Mesenchymal stem cells (MSC) are present in all organs and tissues. Several studies have
shown the therapeutic potential effect of MSC or their derived products. However, the …
shown the therapeutic potential effect of MSC or their derived products. However, the …
Factors involved in cancer metastasis: a better understanding to “seed and soil” hypothesis
Q Liu, H Zhang, X Jiang, C Qian, Z Liu, D Luo - Molecular cancer, 2017 - Springer
Metastasis has intrigued researchers for more than 100 years. Despite the development of
technologies and therapeutic strategies, metastasis is still the major cause of cancer-related …
technologies and therapeutic strategies, metastasis is still the major cause of cancer-related …
The extracellular matrix: its composition, function, remodeling, and role in tumorigenesis
The extracellular matrix (ECM) is a ubiquitous member of the body and is key to the
maintenance of tissue and organ integrity. Initially thought to be a bystander in many cellular …
maintenance of tissue and organ integrity. Initially thought to be a bystander in many cellular …
Exosomes derived from umbilical cord mesenchymal stem cells reduce microglia-mediated neuroinflammation in perinatal brain injury
G Thomi, D Surbek, V Haesler… - Stem cell research & …, 2019 - Springer
Background Preterm newborns are at high risk of develo** neurodevelopmental deficits
caused by neuroinflammation leading to perinatal brain injury. Human Wharton's jelly …
caused by neuroinflammation leading to perinatal brain injury. Human Wharton's jelly …
An update on the progress of isolation, culture, storage, and clinical application of human bone marrow mesenchymal stem/stromal cells
DT Chu, TNT Phuong, NLB Tien, DK Tran… - International journal of …, 2020 - mdpi.com
Bone marrow mesenchymal stem/stromal cells (BMSCs), which are known as multipotent
cells, are widely used in the treatment of various diseases via their self-renewable …
cells, are widely used in the treatment of various diseases via their self-renewable …
Carcinoma-associated mesenchymal stem/stromal cells: architects of the pro-tumorigenic tumor microenvironment
The interaction between tumor cells and non-malignant hosts cells within the tumor
microenvironment (TME) is critical to the pathophysiology of cancer. These non-malignant …
microenvironment (TME) is critical to the pathophysiology of cancer. These non-malignant …
Double‐edged sword of mesenchymal stem cells: cancer‐promoting versus therapeutic potential
HY Lee, IS Hong - Cancer science, 2017 - Wiley Online Library
Mesenchymal stem cells (MSCs) derived from adipose tissue, bone marrow, cord blood, and
other tissues, have recently attracted much attention as potential therapeutic agents in …
other tissues, have recently attracted much attention as potential therapeutic agents in …
Mesenchymal stem cells and cancer: clinical challenges and opportunities
W Lin, L Huang, Y Li, B Fang, G Li… - BioMed research …, 2019 - Wiley Online Library
Stem cell‐based therapies exhibit profound therapeutic potential for treating various human
diseases, including cancer. Among the cell types that can be used for this purpose …
diseases, including cancer. Among the cell types that can be used for this purpose …
Cancer-associated fibroblast heterogeneity: a factor that cannot be ignored in immune microenvironment remodeling
PY Chen, WF Wei, HZ Wu, LS Fan… - Frontiers in immunology, 2021 - frontiersin.org
Cancer-associated fibroblasts (CAFs) are important, highly heterogeneous components of
the tumor extracellular matrix that have different origins and express a diverse set of …
the tumor extracellular matrix that have different origins and express a diverse set of …