Heterocyclic compounds bearing the pyrimidine core are of tremendous interest as they
constitute an important class of natural and synthetic compounds exhibiting diverse useful …

Neurodegenerative diseases are one of the leading causes of mortality worldwide. Currently
available therapeutic agents provide symptomatic relief to a great level. Still, there is a need …

Pyrimidines play an important role in modern medical fields. They have a wide spectrum of
biological activities such as antimicrobial, anticancer, anti-allergic, anti-leishmanial …

A series of heterocyclic compounds with a sulfonamide moiety were synthesized from
reaction of enaminone 4 with active methylene compounds, glycine derivatives, 1, 4 …

Pyrimidine‐based derivatives have attracted a lot of interest in heterocyclic chemistry due to
its versatile structure and diverse biological activities. This study provides a comprehensive …

In the current study, we reported the tandem synthesis of two series of arene-linked
pyrimidinone hybrids with related fused thieno [2, 3-b] pyridine moiety. The target hybrids …

A novel pyrene‐sulfathiazole‐based potential drug candidate 3 was designed, successfully
synthesized by a condensation reaction of pyrenecarboxaldehyde (1) with sulfathiazole (2) …

Pyrimidine-based heterocyclic compounds are garnering substantial interest due to their
essential role as a class of natural and synthetic molecules. These compounds show a …

Pyrrole is a heterocyclic structure with diverse pharmacophores, enabling the creation of an
extensive lead molecule library. Its broad range of pharmacological profiles has concerned …

In this study, we aimed to synthesise and evaluate the antimicrobial activity of
sulphanilamide-condensed pyrimidine derivatives. The compounds were synthesised using …