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Generative models as an emerging paradigm in the chemical sciences
Traditional computational approaches to design chemical species are limited by the need to
compute properties for a vast number of candidates, eg, by discriminative modeling …
compute properties for a vast number of candidates, eg, by discriminative modeling …
Applications of single-cell RNA sequencing in drug discovery and development
B Van de Sande, JS Lee, E Mutasa-Gottgens… - Nature Reviews Drug …, 2023 - nature.com
Single-cell technologies, particularly single-cell RNA sequencing (scRNA-seq) methods,
together with associated computational tools and the growing availability of public data …
together with associated computational tools and the growing availability of public data …
JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles
Abstract JASPAR (https://jaspar. elixir. no/) is a widely-used open-access database
presenting manually curated high-quality and non-redundant DNA-binding profiles for …
presenting manually curated high-quality and non-redundant DNA-binding profiles for …
[HTML][HTML] AI for life: Trends in artificial intelligence for biotechnology
Due to popular successes (eg, ChatGPT) Artificial Intelligence (AI) is on everyone's lips
today. When advances in biotechnology are combined with advances in AI unprecedented …
today. When advances in biotechnology are combined with advances in AI unprecedented …
COSMIC: a curated database of somatic variants and clinical data for cancer
Z Sondka, NB Dhir, D Carvalho-Silva… - Nucleic Acids …, 2024 - academic.oup.com
Abstract The Catalogue Of Somatic Mutations In Cancer (COSMIC), https://cancer. sanger.
ac. uk/cosmic, is an expert-curated knowledgebase providing data on somatic variants in …
ac. uk/cosmic, is an expert-curated knowledgebase providing data on somatic variants in …
RCSB Protein Data Bank (RCSB. org): delivery of experimentally-determined PDB structures alongside one million computed structure models of proteins from …
Abstract The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB
PDB), founding member of the Worldwide Protein Data Bank (wwPDB), is the US data center …
PDB), founding member of the Worldwide Protein Data Bank (wwPDB), is the US data center …
Introducing the bacterial and viral bioinformatics resource center (BV-BRC): a resource combining PATRIC, IRD and ViPR
Abstract The National Institute of Allergy and Infectious Diseases (NIAID) established the
Bioinformatics Resource Center (BRC) program to assist researchers with analyzing the …
Bioinformatics Resource Center (BRC) program to assist researchers with analyzing the …
The ProteomeXchange consortium at 10 years: 2023 update
Mass spectrometry (MS) is by far the most used experimental approach in high-throughput
proteomics. The ProteomeXchange (PX) consortium of proteomics resources (http://www …
proteomics. The ProteomeXchange (PX) consortium of proteomics resources (http://www …
NCBI GEO: archive for gene expression and epigenomics data sets: 23-year update
E Clough, T Barrett, SE Wilhite, P Ledoux… - Nucleic acids …, 2024 - academic.oup.com
Abstract The Gene Expression Omnibus (GEO) is an international public repository that
archives gene expression and epigenomics data sets generated by next-generation …
archives gene expression and epigenomics data sets generated by next-generation …
Traumatic brain injury: progress and challenges in prevention, clinical care, and research
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
neurological disorders, and poses a substantial public health burden. TBI is increasingly …