Generative modeling for RNA splicing code predictions and design

D Wu, A Jha, S Jewell, N Maus, JR Gardner, Y Barash - openreview.net
Alternative splicing (AS) of pre-mRNA splicing is a highly regulated process with diverse
phenotypic effects ranging from changes in AS across tissues to numerous diseases. The …

Prediction of G4 formation in live cells with epigenetic data: a deep learning approach

A Korsakova, AT Phan - NAR Genomics and Bioinformatics, 2023 - academic.oup.com
Abstract G-quadruplexes (G4s) are secondary structures abundant in DNA that may play
regulatory roles in cells. Despite the ubiquity of the putative G-quadruplex-forming …