An ER‐targeted, viscosity‐sensitive hemicyanine dye for the diagnosis of nonalcoholic fatty liver and photodynamic cancer therapy by activating pyroptosis pathway

S Zeng, Y Wang, C Chen, H Kim, X Liu… - Angewandte Chemie …, 2024 - Wiley Online Library
The concept of molecular design, integrating diagnostic and therapeutic functions, aligns
with the general trend of modern medical advancement. Herein, we rationally designed the …

[HTML][HTML] A critical review of the novelties in the development of intravenous nanoemulsions

J Czerniel, A Gostyńska, J Jańczak… - European Journal of …, 2023 - Elsevier
Nanoemulsions have gained increasing attention in recent years as a drug delivery system
due to their ability to improve the solubility and bioavailability of poorly water-soluble drugs …

Oxidative stress in alcoholic liver disease, focusing on proteins, nucleic acids, and lipids: A review

W Lai, J Zhang, J Sun, T Min, Y Bai, J He, H Cao… - International Journal of …, 2024 - Elsevier
Oxidative stress is one of the important factors in the development of alcoholic liver disease.
The production of reactive oxygen species and other free radicals is an important feature of …

Precisely regulating M2 subtype macrophages for renal fibrosis resolution

L Luo, S Wang, Y Hu, L Wang, X Jiang, J Zhang, X Liu… - ACS …, 2023 - ACS Publications
Macrophages are central to the pathogenesis of kidney disease and serve as an effective
therapeutic target for kidney injury and fibrosis. Among them, M2-type macrophages have …

ROS scavenging and immunoregulative EGCG@ Cerium complex loaded in antibacterial polyethylene glycol-chitosan hydrogel dressing for skin wound healing

J Ye, Q Li, Y Zhang, Q Su, Z Feng, P Huang, C Zhang… - Acta biomaterialia, 2023 - Elsevier
The elevation of oxidative stress and inflammatory response after injury remains a
substantial challenge that can deteriorate the wound microenvironment and compromise the …

Association of composite dietary antioxidant index with prevalence of stroke: insights from NHANES 1999-2018

TQ Teng, J Liu, FF Hu, QQ Li, ZZ Hu, Y Shi - Frontiers in immunology, 2024 - frontiersin.org
Background There is a growing acknowledgment of the potential influence of antioxidative
effects resulting from dietary decisions on the occurrence of stroke. The objective of this …

Bruceine A alleviates alcoholic liver disease by inhibiting AIM2 inflammasome activation via activating FXR

L Li, S Xu, W Wang, X Li, H Wang, Q Yang, C Wang… - Phytomedicine, 2024 - Elsevier
Background Alcoholic liver disease (ALD), a public health challenge worldwide caused by
long-term persistent drinking, is life-threatening with minimal approved therapies. Hepatic …

A Novel Endoplasmic Reticulum‐Targeted Metal–Organic Framework–Confined Ruthenium (Ru) Nanozyme Regulation of Oxidative Stress for Central Post‐Stroke …

Q Bai, Y Han, S Khan, T Wu, Y Yang… - Advanced …, 2024 - Wiley Online Library
Central post‐stroke pain (CPSP) is a chronic neuropathic pain caused by cerebrovascular
lesion or disfunction after stroke. Convincing evidence suggest that excessive reactive …

Targeted delivery of food functional ingredients in precise nutrition: design strategy and application of nutritional intervention

X Wang, G Shi, S Fan, J Ma, Y Yan… - Critical Reviews in …, 2024 - Taylor & Francis
With the high incidence of chronic diseases, precise nutrition is a safe and efficient
nutritional intervention method to improve human health. Food functional ingredients are an …

[HTML][HTML] ERRγ-inducible FGF23 promotes alcoholic liver injury through enhancing CYP2E1 mediated hepatic oxidative stress

YS Jung, K Radhakrishnan, S Hammad, S Müller… - Redox Biology, 2024 - Elsevier
Abstract Fibroblast growth factor 23 (FGF23) is a member of endocrine FGF family, along
with FGF15/19 and FGF21. Recent reports showed that under pathological conditions, liver …