Potential therapeutic implications of histidine catabolism by the gut microbiota in NAFLD patients with morbid obesity

S Quesada-Vazquez, A Castells-Nobau, J Latorre… - Cell Reports …, 2023 - cell.com
The gut microbiota contributes to the pathophysiology of non-alcoholic fatty liver disease
(NAFLD). Histidine is a key energy source for the microbiota, scavenging it from the host. Its …

Prevotella copri promotes vascular calcification via lipopolysaccharide through activation of NF-κB signaling pathway

QY Hao, J Yan, JT Wei, YH Zeng, LY Feng, DD Que… - Gut …, 2024 - Taylor & Francis
Emerging evidence indicates that alteration of gut microbiota plays an important role in
chronic kidney disease (CKD)-related vascular calcification (VC). We aimed to investigate …

Nonalcoholic fatty liver disease and the intestinal microbiome: an inseparable link

M Effenberger, C Grander… - Journal of clinical and …, 2023 - pmc.ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) particularly affects patients with type 2 diabetes
and obesity. The incidence of NAFLD has increased significantly over the last decades and …

[HTML][HTML] Gut microbiome and metabolome signatures in liver cirrhosis-related complications

SP Sharma, H Gupta, GH Kwon, SY Lee… - Clinical and …, 2024 - pmc.ncbi.nlm.nih.gov
Background/Aims Shifts in the gut microbiota and metabolites are interrelated with liver
cirrhosis progression and complications. However, causal relationships have not been …

Multiomics analysis reveals the impact of microbiota on host metabolism in hepatic steatosis

M Zeybel, M Arif, X Li, O Altay, H Yang, M Shi… - Advanced …, 2022 - Wiley Online Library
Metabolic dysfunction‐associated fatty liver disease (MAFLD) is a complex disease
involving alterations in multiple biological processes regulated by the interactions between …

The gut microbiota: A new perspective for tertiary prevention of hepatobiliary and gallbladder diseases

X Huang, Y Yang, X Li, X Zhu, D Lin, Y Ma… - Frontiers in …, 2023 - frontiersin.org
The gut microbiota is a complex ecosystem that has coevolved with the human body for
hundreds of millions of years. In the past 30 years, with the progress of gene sequencing …

Impaired flux of bile acids from the liver to the gut reveals microbiome-immune interactions associated with liver damage

H Leung, L **ong, Y Ni, A Busch, M Bauer… - npj Biofilms and …, 2023 - nature.com
Currently, there is evidence that alteration in the gut ecosystem contributes to the
development of liver diseases, however, the complex mechanisms involved are still unclear …

[HTML][HTML] Microbiota dysbiosis and gut barrier dysfunction associated with non-alcoholic fatty liver disease are modulated by a specific metabolic cofactors' combination

S Quesada-Vázquez, C Bone, S Saha… - International Journal of …, 2022 - mdpi.com
The gut is a selective barrier that not only allows the translocation of nutrients from food, but
also microbe-derived metabolites to the systemic circulation that flows through the liver …

A metagenomic study identifies a Prevotella copri enriched microbial profile associated with non‐alcoholic steatohepatitis in subjects with obesity

S Moran‐Ramos, D Cerqueda‐García… - Journal of …, 2023 - Wiley Online Library
Abstract Background and Aim Non‐alcoholic fatty liver disease (NAFLD) is the most
common cause of liver disease. Increasing evidence indicates that the gut microbiota can …

[HTML][HTML] The effects of alcohol drinking on oral microbiota in the Chinese population

Y Liao, XT Tong, YJ Jia, QY Liu, YX Wu… - International Journal of …, 2022 - mdpi.com
The dysbiosis of oral microbiota is linked to numerous diseases and is associated with
personal lifestyles, such as alcohol drinking. However, there is inadequate data to study the …