Candida auris: Epidemiology, biology, antifungal resistance, and virulence

H Du, J Bing, T Hu, CL Ennis, CJ Nobile… - PLoS …, 2020 - journals.plos.org
First described in 2009 in Japan, the emerging multidrug-resistant fungal pathogen Candida
auris is becoming a worldwide public health threat that has been attracting considerable …

[HTML][HTML] Molecular Mechanisms Associated with Antifungal Resistance in Pathogenic Candida Species

KM Czajka, K Venkataraman, D Brabant-Kirwan… - Cells, 2023 - mdpi.com
Candidiasis is a highly pervasive infection posing major health risks, especially for
immunocompromised populations. Pathogenic Candida species have evolved intrinsic and …

Refactored genetic codes enable bidirectional genetic isolation

JF Zürcher, WE Robertson, T Kappes, G Petris… - Science, 2022 - science.org
The near-universal genetic code defines the correspondence between codons in genes and
amino acids in proteins. We refactored the structure of the genetic code in Escherichia coli …

Comparative genomics of biotechnologically important yeasts

R Riley, S Haridas, KH Wolfe, MR Lopes… - Proceedings of the …, 2016 - pnas.org
Ascomycete yeasts are metabolically diverse, with great potential for biotechnology. Here,
we report the comparative genome analysis of 29 taxonomically and biotechnologically …

Clinical isolates of Candida auris with enhanced adherence and biofilm formation due to genomic amplification of ALS4

J Bing, Z Guan, T Zheng, Z Zhang, S Fan… - PLoS …, 2023 - journals.plos.org
Candida auris is an emerging multidrug-resistant fungal pathogen and a new global threat
to human health. A unique morphological feature of this fungus is its multicellular …

Candida haemulonii Complex and Candida auris: Biology, Virulence Factors, Immune Response, and Multidrug Resistance

M Gómez-Gaviria, JA Martínez-Álvarez… - Infection and drug …, 2023 - Taylor & Francis
There is worldwide concern about the constant increase in infections caused by Candida
species that are multiresistant to antifungal drugs. The most common candidiasis is caused …

Candida survival strategies

M Polke, B Hube, ID Jacobsen - Advances in Applied Microbiology, 2015 - Elsevier
Only few Candida species, eg, Candida albicans, Candida glabrata, Candida dubliniensis,
and Candida parapsilosis, are successful colonizers of a human host. Under certain …

Synergy between sequence and size in large-scale genomics

TR Gregory - Nature Reviews Genetics, 2005 - nature.com
Until recently the study of individual DNA sequences and of total DNA content (the C-value)
sat at opposite ends of the spectrum in genome biology. For gene sequencers, the vast …

Nine Things Genomics Can Tell Us About Candida auris

AD Chybowska, DS Childers, RA Farrer - Frontiers in genetics, 2020 - frontiersin.org
Candida auris is a recently emerged multidrug-resistant fungal pathogen causing severe
illness in hospitalized patients. C. auris is most closely related to a few environmental or …

Genome diversity and evolution in the budding yeasts (Saccharomycotina)

BA Dujon, EJ Louis - Genetics, 2017 - academic.oup.com
Considerable progress in our understanding of yeast genomes and their evolution has been
made over the last decade with the sequencing, analysis, and comparisons of numerous …