Gradual degeneration and loss of dopaminergic neurons in the substantia nigra, pars
compacta and subsequent reduction of dopamine levels in striatum are associated with …

An extensive body of research suggests the spontaneous eye blink rate (EBR) is a non-
invasive indirect marker of central dopamine (DA) function, with higher EBR predicting …

Mitochondrial dysfunction and oxidative stress characterize major factors involved in the
activation of complex processes corresponding to apoptosis‐mediated neuronal …

Although the global prevalence of neurological disorders such as Parkinson's disease,
Alzheimer's disease, glioblastoma, epilepsy, and multiple sclerosis is steadily increasing …

The phytocannabinoids of Cannabis sativa L. have, since ancient times, been proposed as a
pharmacological alternative for treating various central nervous system (CNS) disorders …

Various surgical techniques and pharmaceutical treatments have been developed to
improve the current technologies of treating brain diseases. Focused ultrasound (FUS) is a …

Parkinson's disease (PD) is a progressive neurological disorder of the central nervous
system that deteriorates motor functions, while it is also accompanied by a large diversity of …

Background Parkinson's disease (PD) is a common neurodegenerative condition associated
with a wide range of motor and non-motor symptoms. There has been increasing interest in …

Symptoms of Parkinson's disease have been controlled with levodopa for many years;
however, motor complications consisting of wearing off of medication effect and dyskinesias …

The basal ganglia network serves to integrate information about context, actions, and
outcomes to shape the behavior of an animal based on its past experience. Clinically, the …