Fundamental Neurochemistry Review: Microglial immunometabolism in traumatic brain injury
Traumatic brain injury (TBI) is a devastating neurological disorder caused by a physical
impact to the brain that promotes diffuse damage and chronic neurodegeneration. Key …
impact to the brain that promotes diffuse damage and chronic neurodegeneration. Key …
[HTML][HTML] A tutorial on optical photothermal infrared (O-PTIR) microscopy
This tutorial reviews the rapidly growing field of optical photothermal infrared (O-PTIR)
spectroscopy and chemical imaging. O-PTIR is an infrared super-resolution measurement …
spectroscopy and chemical imaging. O-PTIR is an infrared super-resolution measurement …
Single-cell map** of lipid metabolites using an infrared probe in human-derived model systems
Understanding metabolic heterogeneity is the key to uncovering the underlying mechanisms
of metabolic-related diseases. Current metabolic imaging studies suffer from limitations …
of metabolic-related diseases. Current metabolic imaging studies suffer from limitations …
Label-Free High-Resolution Photothermal Optical Infrared Spectroscopy for Spatiotemporal Chemical Analysis in Fresh, Hydrated Living Tissues and Embryos
Label-free chemical imaging of living and functioning systems is the holy grail of
biochemical research. However, existing techniques often require extensive sample …
biochemical research. However, existing techniques often require extensive sample …
Monitoring Phenotype Heterogeneity at the Single-Cell Level within Bacillus Populations Producing Poly-3-hydroxybutyrate by Label-Free Super-resolution Infrared …
Phenotypic heterogeneity is commonly found among bacterial cells within microbial
populations due to intrinsic factors as well as equip** the organisms to respond to …
populations due to intrinsic factors as well as equip** the organisms to respond to …
Structural Map** of Protein Aggregates in Live Cells Modeling Huntington's Disease
While protein aggregation is a hallmark of many neurodegenerative diseases, acquiring
structural information on protein aggregates inside live cells remains challenging …
structural information on protein aggregates inside live cells remains challenging …
[HTML][HTML] 3D micro-CT and O-PTIR spectroscopy bring new understanding of the influence of filler content in dental resin composites
Background Dental resin composites' performance is intricately linked to their polymerisation
shrinkage characteristics. This study compares polymerisation shrinkage using advanced …
shrinkage characteristics. This study compares polymerisation shrinkage using advanced …
Precision proteoform design for 4R tau isoform selective templated aggregation
AP Longhini, A DuBose, S Lobo… - Proceedings of the …, 2024 - National Acad Sciences
Prion-like spread of disease-specific tau conformers is a hallmark of all tauopathies. A 19-
residue probe peptide containing a P301L mutation and spanning the R2/R3 splice junction …
residue probe peptide containing a P301L mutation and spanning the R2/R3 splice junction …
Mid-infrared Photothermal Imaging: Instrument and Life Science Applications
Understanding biological processes at the molecular level is crucial for advancements in life
science, including disease diagnosis, pharmacology, and biotechnology. Visualizing …
science, including disease diagnosis, pharmacology, and biotechnology. Visualizing …
Spatially Resolved Near Field Spectroscopy of Vibrational Polaritons at the Small N Limit
O Hirschmann, HH Bhakta, WJM Kort-Kamp… - ACS …, 2024 - ACS Publications
Vibrational polaritons, which have been primarily studied in Fabry–Pérot cavities with a
large number of molecules (N∼ 106–1010) coupled to the resonator mode, exhibit various …
large number of molecules (N∼ 106–1010) coupled to the resonator mode, exhibit various …