Cytotoxic activity and molecular modeling of progestins, pregna-D′-pentaranes

Selective ligands of membrane progesterone receptors as a key to studying their biological functions in vitro and in vivo

IS Levina, YV Kuznetsov, TA Shchelkunova… - The Journal of Steroid …, 2021 - Elsevier
Progesterone modulates many processes in the body, acting through nuclear receptors
(nPR) in various organs and tissues. However, a number of effects are mediated by …
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New estrogen receptor antagonists. 3, 20-Dihydroxy-19-norpregna-1, 3, 5 (10)-trienes: Synthesis, molecular modeling, and biological evaluation

YV Kuznetsov, IS Levina, AM Scherbakov… - European journal of …, 2018 - Elsevier
New estrogen receptor α (ERα) antagonists–3, 20-dihydroxy-19-norpregna-1, 3, 5 (10)-
trienes containing an additional carbocyclic ring D′ at the 16α, 17α positions–were …
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