Coarse-grained protein models and their applications

S Kmiecik, D Gront, M Kolinski, L Wieteska… - Chemical …, 2016 - ACS Publications
The traditional computational modeling of protein structure, dynamics, and interactions
remains difficult for many protein systems. It is mostly due to the size of protein …

Protein ensembles: how does nature harness thermodynamic fluctuations for life? The diverse functional roles of conformational ensembles in the cell

G Wei, W ** in the NF-κB/IκB/DNA genetic regulatory network
DA Potoyan, W Zheng, EA Komives… - Proceedings of the …, 2016 - pnas.org
Genetic switches based on the NF-κ B/I κ B/DNA system are master regulators of an array of
cellular responses. Recent kinetic experiments have shown that I κ B can actively remove …