The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications

B Zingales, MA Miles, DA Campbell… - Infection, genetics and …, 2012 - Elsevier
The protozoan Trypanosoma cruzi, its mammalian reservoirs, and vectors have existed in
nature for millions of years. The human infection, named Chagas disease, is a major public …

Current drug therapy and pharmaceutical challenges for Chagas disease

J Bermudez, C Davies, A Simonazzi, JP Real, S Palma - Acta tropica, 2016 - Elsevier
One of the most significant health problems in the American continent in terms of human
health, and socioeconomic impact is Chagas disease, caused by the protozoan parasite …

[BOOK][B] Molecular markers, natural history and evolution

JC Avise - 2012 - books.google.com
Molecular approaches have opened new windows on a host of ecological and evolutionary
disciplines, ranging from population genetics and behavioral ecology to conservation …

[HTML][HTML] A new consensus for Trypanosoma cruzi intraspecific nomenclature: second revision meeting recommends TcI to TcVI

B Zingales, SG Andrade, MRS Briones… - Memórias do Instituto …, 2009 - SciELO Brasil
In an effort to unify the nomenclature of Trypanosoma cruzi, the causative agent of Chagas
disease, an updated system was agreed upon at the Second Satellite Meeting. A consensus …

DNA markers define two major phylogenetic lineages of Trypanosoma cruzi

RP Souto, O Fernandes, AM Macedo… - Molecular and …, 1996 - Elsevier
Parasitic protozoa within the taxon Trypanosoma cruzi are considered to be derived from
multiple clonal lineages, and show broad genetic diversity as a result of propagation with …

[BOOK][B] Evolution through genetic exchange

ML Arnold - 2006 - books.google.com
Even before the publication of Darwin's Origin of Species, the perception of evolutionary
change has been a tree-like pattern of diversification-with divergent branches spreading …

A clonal theory of parasitic protozoa: the population structures of Entamoeba, Giardia, Leishmania, Naegleria, Plasmodium, Trichomonas, and Trypanosoma and their …

M Tibayrenc, F Kjellberg… - Proceedings of the …, 1990 - National Acad Sciences
We propose a general theory of clonal reproduction for parasitic protozoa, which has
important medical and biological consequences. Many parasitic protozoa have been …

[BOOK][B] Immunology and evolution of infectious disease

SA Frank - 2002 - degruyter.com
From HIV to influenza, the battle between infectious agents and the immune system is at the
heart of disease. Knowledge of how and why parasites vary to escape recognition by the …

Trypanosoma cruzi: genetic structure of populations and relevance of genetic variability to the pathogenesis of Chagas disease

AM Macedo, CR Machado, RP Oliveira… - Memorias do Instituto …, 2004 - SciELO Brasil
Chagas disease, caused by the protozoan Trypanosoma cruzi, has a variable clinical
course, ranging from symptomless infection to severe chronic disease with cardiovascular or …

[HTML][HTML] Trypanosoma cruzi: adaptation to its vectors and its hosts

F Noireau, P Diosque, AM Jansen - Veterinary research, 2009 - ncbi.nlm.nih.gov
American trypanosomiasis is a parasitic zoonosis that occurs throughout Latin America. The
etiological agent, Trypanosoma cruzi, is able to infect almost all tissues of its mammalian …