Advances in optical manipulation and observation of neural activity have set the stage for
widespread implementation of closed-loop and activity-guided optical control of neural …

Neural circuitry has evolved to form distributed networks that act dynamically across large
volumes. Conventional microscopy collects data from individual planes and cannot sample …

When experts are immersed in a task, do their brains prioritize task-related activity? Most
efforts to understand neural activity during well-learned tasks focus on cognitive …

INTRODUCTION Perceptual experiences in mammals may arise from patterns of neural
circuit activity in cerebral cortex. For example, primary visual cortex (V1) is causally capable …

Circuits in the cerebral cortex consist of thousands of neurons connected by millions of
synapses. A precise understanding of these local networks requires relating circuit activity …

Neuronal representations change as associations are learned between sensory stimuli and
behavioral actions. However, it is poorly understood whether representations for learned …

To understand how the brain processes sensory information to guide behavior, we must
know how stimulus representations are transformed throughout the visual cortex. Here we …

The cortical population code is pervaded by activity patterns evoked by movement, but it
remains largely unknown how such signals relate to natural behavior or how they might …

Two-photon calcium imaging provides an optical readout of neuronal activity in populations
of neurons with subcellular resolution. However, conventional two-photon imaging systems …

The mechanistic link between neural circuit activity and behavior remains unclear. While
manipulating cortical activity can bias certain behaviors and elicit artificial percepts, some …