[HTML][HTML] Lipid nanoparticles as delivery vehicles for inhaled therapeutics

EWX Leong, R Ge - Biomedicines, 2022 - mdpi.com
Lipid nanoparticles (LNPs) have emerged as a powerful non-viral carrier for drug delivery.
With the prevalence of respiratory diseases, particularly highlighted by the current COVID-19 …

Nanoparticle-based drug delivery system: the magic bullet for the treatment of chronic pulmonary diseases

S Pramanik, S Mohanto, R Manne… - Molecular …, 2021 - ACS Publications
Chronic pulmonary diseases encompass different persistent and lethal diseases, including
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …

Solid lipid nanoparticles for targeted natural and synthetic drugs delivery in high-incidence cancers, and other diseases: Roles of preparation methods, lipid …

HA Mohammed, RA Khan, V Singh, M Yusuf… - Nanotechnology …, 2023 - degruyter.com
Solid lipid nanoparticles (SLNs), the spheroidal-shaped, colloids state lipophilic-natured,
innovative nanoscale particulate materials, are being concurrently prepared by the quality …

Inhalable nanoparticle-based dry powder formulations for respiratory diseases: challenges and strategies for translational research

HW Chan, S Chow, X Zhang, Y Zhao, HHY Tong… - AAPS …, 2023 - Springer
The emergence of novel respiratory infections (eg, COVID-19) and expeditious development
of nanoparticle-based COVID-19 vaccines have recently reignited considerable interest in …

Progress of gelatin-based microspheres (GMSs) as delivery vehicles of drug and cell

Z Dong, X Meng, W Yang, J Zhang, P Sun… - Materials Science and …, 2021 - Elsevier
Gelatin has various attractive features as biomedical materials, for instance, biocompatibility,
low immunogenicity, biodegradability, and ease of manipulation. In recent years, various …

[HTML][HTML] Solid lipid nanoparticles

TTL Nguyen, VA Duong - Encyclopedia, 2022 - mdpi.com
Definition Solid lipid nanoparticles (SLNs) are produced from physiologically biocompatible
lipids. They have been proven to improve solubility, cellular uptake, and stability, reduce …

Gefitinib: an updated review of its role in the cancer management, its nanotechnological interventions, recent patents and clinical trials

P Kumar, B Mangla, S Javed, W Ahsan… - Recent patents on …, 2023 - benthamdirect.com
Background: Gefitinib, a tyrosine kinase inhibitor, is effectively used in the targeted treatment
of malignant conditions. It suppresses the signal transduction cascades leading to cell …

[HTML][HTML] Development of a new inhaled swellable microsphere system for the dual delivery of naringenin-loaded solid lipid nanoparticles and doxofylline for the …

A Pareek, R Kothari, A Pareek, Y Ratan… - European Journal of …, 2024 - Elsevier
This study developed a new dual delivery system of naringenin (NRG), a polyphenol, and
doxofylline (DOX), a xanthine derivative, as an inhaled microsphere system. In this system …

Evaluation of thermosensitive chitosan hydrogel containing gefitinib loaded cellulose acetate butyrate nanoparticles in a subcutaneous breast cancer model

Z Karimi, S Taymouri, M Minaiyan, M Mirian - International Journal of …, 2022 - Elsevier
In the present study, gefitinib loaded cellulose acetate butyrate nanoparticles (Gnb-NPs)
were prepared and then incorporated into thermo-sensitive chitosan/β-glycerophosphate …

A nanotechnology driven effectual localized lung cancer targeting approaches using tyrosine kinases inhibitors: Recent progress, preclinical assessment, challenges …

A Kumar, KK Vaiphei, A Gulbake - International Journal of Pharmaceutics, 2024 - Elsevier
The higher incidence and mortality rate among all populations worldwide explains the
unmet solutions in the treatment of lung cancer. The evolution of targeted therapies using …