The prevalence of obesity has reached pandemic proportions, and now approximately 25%
of adults in Westernized countries have obesity. Recognized as a major health concern …

Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

The exclusion of other chronic liver diseases including “excess” alcohol intake has until now
been necessary to establish a diagnosis of metabolic dysfunction-associated fatty liver …

Obesity contributes to reduced life expectancy, impaired quality of life, and disabilities,
mainly in those individuals who develop cardiovascular diseases, type 2 diabetes …

In Japan, a super-aged society, deaths from atherosclerotic cardiovascular disease
(ASCVD), especially cardiac diseases including coronary artery disease (CAD) such as …

An increase in fat mass is considered to be an important risk factor for the worldwide
increase in type 2 diabetes and cardiovascular disease. However, for a given fat mass, there …

Fatty liver associated with metabolic dysfunction is common, affects a quarter of the
population, and has no approved drug therapy. Although pharmacotherapies are in …

Obesity is the most extended metabolic alteration worldwide increasing the risk for the
development of cardiometabolic alterations such as type 2 diabetes, hypertension, and …

The concept of metabolic health, particularly in obesity, has attracted a lot of attention in the
scientific community, and is being increasingly used to determine the risk of cardiovascular …

Although obesity is typically associated with metabolic dysfunction and cardiometabolic
diseases, some people with obesity are protected from many of the adverse metabolic …