Macromolecular modeling and design in Rosetta: recent methods and frameworks
The Rosetta software for macromolecular modeling, docking and design is extensively used
in laboratories worldwide. During two decades of development by a community of …
in laboratories worldwide. During two decades of development by a community of …
Coarse-grained protein models and their applications
The traditional computational modeling of protein structure, dynamics, and interactions
remains difficult for many protein systems. It is mostly due to the size of protein …
remains difficult for many protein systems. It is mostly due to the size of protein …
Nanodiscs in membrane biochemistry and biophysics
Membrane proteins play a most important part in metabolism, signaling, cell motility,
transport, development, and many other biochemical and biophysical processes which …
transport, development, and many other biochemical and biophysical processes which …
Lipid–protein interactions are unique fingerprints for membrane proteins
Cell membranes contain hundreds of different proteins and lipids in an asymmetric
arrangement. Our current understanding of the detailed organization of cell membranes …
arrangement. Our current understanding of the detailed organization of cell membranes …
CG2AT2: an enhanced fragment-based approach for serial multi-scale molecular dynamics simulations
Coarse-grained molecular dynamics provides a means for simulating the assembly and
interactions of macromolecular complexes at a reduced level of representation, thereby …
interactions of macromolecular complexes at a reduced level of representation, thereby …
[BOOK][B] Introduction to proteins: structure, function, and motion
Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the
structure, function, and motion of proteins for students, faculty, and researchers at all levels …
structure, function, and motion of proteins for students, faculty, and researchers at all levels …
An integrated framework advancing membrane protein modeling and design
Membrane proteins are critical functional molecules in the human body, constituting more
than 30% of open reading frames in the human genome. Unfortunately, a myriad of …
than 30% of open reading frames in the human genome. Unfortunately, a myriad of …
[HTML][HTML] Membrane proteins structures: A review on computational modeling tools
Abstract Background Membrane proteins (MPs) play diverse and important functions in
living organisms. They constitute 20% to 30% of the known bacterial, archaean and …
living organisms. They constitute 20% to 30% of the known bacterial, archaean and …
Determinants of endoplasmic reticulum-to-lipid droplet protein targeting
Lipid droplet (LD) formation from the endoplasmic reticulum (ER) is accompanied by the
targeting and accumulation of specific hydrophobic, membrane-embedded proteins on LDs …
targeting and accumulation of specific hydrophobic, membrane-embedded proteins on LDs …
Endogenous ion channels expressed in human embryonic kidney (HEK-293) cells
J Zhang, H Yuan, X Yao, S Chen - Pflügers Archiv-European Journal of …, 2022 - Springer
Mammalian expression systems, particularly the human embryonic kidney (HEK-293) cells,
combined with electrophysiological studies, have greatly benefited our understanding of the …
combined with electrophysiological studies, have greatly benefited our understanding of the …