Toward predictive multiscale modeling of vascular tumor growth: computational and experimental oncology for tumor prediction

JT Oden, EABF Lima, RC Almeida, Y Feng… - … Methods in Engineering, 2016 - Springer
New directions in medical and biomedical sciences have gradually emerged over recent
years that will change the way diseases are diagnosed and treated and are leading to the …

Optimal control for a nonlinear stochastic PDE model of cancer growth

S Esmaili, MR Eslahchi, DFM Torres - Optimization, 2024 - Taylor & Francis
We study an optimal control problem for a stochastic model of tumour growth with drug
application. This model consists of three stochastic hyperbolic equations describing the …

Analysis and numerical solution of stochastic phase‐field models of tumor growth

EABF Lima, RC Almeida… - Numerical methods for …, 2015 - Wiley Online Library
Carcinogenesis, as every biological process, is not purely deterministic as all systems are
subject to random perturbations from the environment. In tumor growth models, the values of …

Estimating and determining the effect of a therapy on tumor dynamics by means of a modified Gompertz diffusion process

G Albano, V Giorno, P Román-Román… - Journal of theoretical …, 2015 - Elsevier
A modified Gompertz diffusion process is considered to model tumor dynamics. The
infinitesimal mean of this process includes non-homogeneous terms describing the effect of …

Inference on an heteroscedastic Gompertz tumor growth model

G Albano, V Giorno, P Román-Román… - Mathematical …, 2020 - Elsevier
We consider a non homogeneous Gompertz diffusion process whose parameters are
modified by generally time-dependent exogenous factors included in the infinitesimal …

Estimating a non-homogeneous Gompertz process with jumps as model of tumor dynamics

V Giorno, P Román-Román, S Spina… - … Statistics & Data Analysis, 2017 - Elsevier
A non-homogeneous stochastic model based on a Gompertz-type diffusion process with
jumps is proposed to describe the evolution of a solid tumor subject to an intermittent …

On the effect of a therapy able to modify both the growth rates in a Gompertz stochastic model

G Albano, V Giorno, P Román-Román… - Mathematical …, 2013 - Elsevier
A Gompertz-type diffusion process characterized by the presence of exogenous factors in
the drift term is considered. Such a process is able to describe the dynamics of populations …

A stochastic model of cancer growth subject to an intermittent treatment with combined effects: Reduction in tumor size and rise in growth rate

S Spina, V Giorno, P Román-Román… - Bulletin of mathematical …, 2014 - Springer
A model of cancer growth based on the Gompertz stochastic process with jumps is proposed
to analyze the effect of a therapeutic program that provides intermittent suppression of …

A stochastic Gompertz model with logarithmic therapy functions: Parameters estimation

R Gutiérrez, R Gutiérrez-Sanchez - Applied Mathematics and …, 2012 - Elsevier
This paper is concerned with the estimation of the parameters of interest in the drift
coefficient of a stochastic Gompertz model with logarithmic therapeutic functions. The …

A stochastic Gompertz model highlighting internal and external therapy function for tumour growth

R Gutiérrez-Sanchez, MC Melchor… - Applied Mathematics …, 2014 - Elsevier
This paper proposes a model of tumour cell growth based on a Gompertz-type
nonhomogeneous stochastic diffusion, whose drift coefficient depends on two functions of …