Non-viral vectors for RNA delivery
Y Yan, XY Liu, A Lu, XY Wang, LX Jiang… - Journal of Controlled …, 2022 - Elsevier
RNA-based therapy is a promising and potential strategy for disease treatment by
introducing exogenous nucleic acids such as messenger RNA (mRNA), small interfering …
introducing exogenous nucleic acids such as messenger RNA (mRNA), small interfering …
[HTML][HTML] Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis
M Zhao, R Wang, K Yang, Y Jiang, Y Peng, Y Li… - … Pharmaceutica Sinica B, 2023 - Elsevier
RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …
A lysosome‐activated tetrahedral nanobox for encapsulated siRNA delivery
Y Gao, X Chen, T Tian, T Zhang, S Gao… - Advanced …, 2022 - Wiley Online Library
Tetrahedral framework nucleic acids (tFNAs) have attracted extensive attention as drug
nanocarriers because of their excellent cellular uptake. However, for oligonucleotide cargos …
nanocarriers because of their excellent cellular uptake. However, for oligonucleotide cargos …
Liposome-based delivery of biological drugs
Biological drugs are attracting tremendous attention in disease treatment. However, their
application is significantly limited by their inherent properties, such as high hydrophilicity …
application is significantly limited by their inherent properties, such as high hydrophilicity …
A review of advanced multifunctional magnetic nanostructures for cancer diagnosis and therapy integrated into an artificial intelligence approach
The new era of nanomedicine offers significant opportunities for cancer diagnostics and
treatment. Magnetic nanoplatforms could be highly effective tools for cancer diagnosis and …
treatment. Magnetic nanoplatforms could be highly effective tools for cancer diagnosis and …
Phototheranostics for multifunctional treatment of cancer with fluorescence imaging
X Yin, Y Cheng, Y Feng, WR Stiles, SH Park… - Advanced drug delivery …, 2022 - Elsevier
Phototheranostics stem from the recent advances in nanomedicines and bioimaging to
diagnose and treat human diseases. Since tumors' diversity, heterogeneity, and instability …
diagnose and treat human diseases. Since tumors' diversity, heterogeneity, and instability …
Emerging nanotechnology-based therapeutics to combat multidrug-resistant cancer
Cancer often develops multidrug resistance (MDR) when cancer cells become resistant to
numerous structurally and functionally different chemotherapeutic agents. MDR is …
numerous structurally and functionally different chemotherapeutic agents. MDR is …
[HTML][HTML] Nano-scale delivery systems for siRNA delivery in cancer therapy: New era of gene therapy empowered by nanotechnology
N Ebrahimi, MS Manavi, A Nazari, A Momayezi… - Environmental …, 2023 - Elsevier
RNA interference (RNAi) is a unique treatment approach used to decrease a disease's
excessive gene expression, including cancer. SiRNAs may find and destroy homologous …
excessive gene expression, including cancer. SiRNAs may find and destroy homologous …
Hybrid lipid/polymer nanoparticles to tackle the cystic fibrosis mucus barrier in siRNA delivery to the lungs: does PEGylation make the difference?
Inhaled siRNA therapy has a unique potential for treatment of severe lung diseases, such as
cystic fibrosis (CF). Nevertheless, a drug delivery system tackling lung barriers is mandatory …
cystic fibrosis (CF). Nevertheless, a drug delivery system tackling lung barriers is mandatory …
Cancer chemoresistance and its mechanisms: Associated molecular factors and its regulatory role
S Kannampuzha, AV Gopalakrishnan - Medical Oncology, 2023 - Springer
Cancer therapy has advanced from tradition chemotherapy methods to targeted therapy,
novel drug delivery mechanisms, combination therapies etc. Although several novel …
novel drug delivery mechanisms, combination therapies etc. Although several novel …