Non-viral vectors for RNA delivery

Y Yan, XY Liu, A Lu, XY Wang, LX Jiang… - Journal of Controlled …, 2022 - Elsevier
RNA-based therapy is a promising and potential strategy for disease treatment by
introducing exogenous nucleic acids such as messenger RNA (mRNA), small interfering …

[HTML][HTML] Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis

M Zhao, R Wang, K Yang, Y Jiang, Y Peng, Y Li… - … Pharmaceutica Sinica B, 2023 - Elsevier
RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …

A lysosome‐activated tetrahedral nanobox for encapsulated siRNA delivery

Y Gao, X Chen, T Tian, T Zhang, S Gao… - Advanced …, 2022 - Wiley Online Library
Tetrahedral framework nucleic acids (tFNAs) have attracted extensive attention as drug
nanocarriers because of their excellent cellular uptake. However, for oligonucleotide cargos …

Liposome-based delivery of biological drugs

KT Magar, GF Boafo, X Li, Z Chen, W He - Chinese Chemical Letters, 2022 - Elsevier
Biological drugs are attracting tremendous attention in disease treatment. However, their
application is significantly limited by their inherent properties, such as high hydrophilicity …

A review of advanced multifunctional magnetic nanostructures for cancer diagnosis and therapy integrated into an artificial intelligence approach

B Govindan, MA Sabri, A Hai, F Banat, MA Haija - Pharmaceutics, 2023 - mdpi.com
The new era of nanomedicine offers significant opportunities for cancer diagnostics and
treatment. Magnetic nanoplatforms could be highly effective tools for cancer diagnosis and …

Phototheranostics for multifunctional treatment of cancer with fluorescence imaging

X Yin, Y Cheng, Y Feng, WR Stiles, SH Park… - Advanced drug delivery …, 2022 - Elsevier
Phototheranostics stem from the recent advances in nanomedicines and bioimaging to
diagnose and treat human diseases. Since tumors' diversity, heterogeneity, and instability …

Emerging nanotechnology-based therapeutics to combat multidrug-resistant cancer

P Yadav, SV Ambudkar, N Rajendra Prasad - Journal of …, 2022 - Springer
Cancer often develops multidrug resistance (MDR) when cancer cells become resistant to
numerous structurally and functionally different chemotherapeutic agents. MDR is …

[HTML][HTML] Nano-scale delivery systems for siRNA delivery in cancer therapy: New era of gene therapy empowered by nanotechnology

N Ebrahimi, MS Manavi, A Nazari, A Momayezi… - Environmental …, 2023 - Elsevier
RNA interference (RNAi) is a unique treatment approach used to decrease a disease's
excessive gene expression, including cancer. SiRNAs may find and destroy homologous …

Hybrid lipid/polymer nanoparticles to tackle the cystic fibrosis mucus barrier in siRNA delivery to the lungs: does PEGylation make the difference?

G Conte, G Costabile, D Baldassi… - … Applied Materials & …, 2022 - ACS Publications
Inhaled siRNA therapy has a unique potential for treatment of severe lung diseases, such as
cystic fibrosis (CF). Nevertheless, a drug delivery system tackling lung barriers is mandatory …

Cancer chemoresistance and its mechanisms: Associated molecular factors and its regulatory role

S Kannampuzha, AV Gopalakrishnan - Medical Oncology, 2023 - Springer
Cancer therapy has advanced from tradition chemotherapy methods to targeted therapy,
novel drug delivery mechanisms, combination therapies etc. Although several novel …