Curcumin based pyrazole-thiazole hybrids as antiproliferative agents: Synthesis, pharmacokinetic, photophysical properties, and docking studies

R Palabindela, R Guda, G Ramesh, R Bodapati… - Journal of Molecular …, 2023 - Elsevier
A series of new curcumin pyrazole-thiazole hybrids (C 1-C 8) were synthesized and
characterized by fundamental spectral analysis. The synthesized compounds were tested for …

Dual state emissive tridentate imidazopyridines with applications in acidochromism, metal ions detection, data encryption, and bioimaging

Z Meng, Y Li, K Liao, Y Sun, W Zhang, B Song, X Zhu… - Dyes and …, 2024 - Elsevier
Four novel tridentate scaffolds IP-nTPA (n= 1, 4, 8, and 12), in which 2, 6-bis (imidazo [1, 2-a]
pyridin-2-yl) pyridine and alkoxyl-substituted triphenylamine (TPA) are utilized as electron …

One-pot multicomponent synthesis of novel pyridine derivatives for antidiabetic and antiproliferative activities

N Shafiq, N Shahzad, F Rida, Z Ahmad… - Future Medicinal …, 2023 - Taylor & Francis
Background: Due to the close relationship of diabetes with hypertension reported in various
research, a set of pyridine derivatives with US FDA-approved drug cores were designed and …

Structure-dependent and environment-responsive optical properties of the trisheterocyclic systems with electron donating amino groups

J Palion-Gazda, B Machura, T Klemens… - Dyes and …, 2019 - Elsevier
Abstract A series of 2, 2′: 6′, 2 ″-terpyridine (terpy), 2, 6-di (thiazol-2-yl) pyridine (dtpy),
and 2, 6-di (pyrazin-2-yl) pyridine (dppy) derivatives with electron donating amino groups …

Construction of spin crossover-fluorescence bifunctional iron (ii) complexes with modified bis (pyrazole) pyridine ligands

GH Zhao, SH Zhang, C Yi, T Liu, YS Meng - New Journal of Chemistry, 2023 - pubs.rsc.org
The design and construction of bifunctional molecular materials combined with spin
crossover (SCO) and fluorescence have become a hot topic in magnetic materials research …

Tuning Optical Properties of Re (I) Carbonyl Complexes by Modifying Push–Pull Ligands Structure

T Klemens, A Switlicka, A Szlapa-Kula, Ł Łapok… - …, 2019 - ACS Publications
In this work, the structure–property relationship was investigated for a series of Re (I)
carbonyls [ReCl (CO) 3 (R-terpy-κ2N)],[ReCl (CO) 3 (R-dtpy-κ2N)], and [ReCl (CO) 3 (R …

A Novel Multi-Effect Photosensitizer for Tumor Destruction via Multimodal Imaging Guided Synergistic Cancer Phototherapy

K Sun, B Wang, M Li, Y Ge, L An, D Zeng… - International Journal …, 2024 - Taylor & Francis
Background How to ingeniously design multi-effect photosensitizers (PSs), including
multimodal imaging and multi-channel therapy, is of great significance for highly …

Synthesis, docking studies, in silico ADMET predictions, DFT calculations, and photophysical properties of thiazole-anthracene hybrids as potent EGFR inhibitors

R Palabindela, R Bodapati, P Myadaraveni… - Journal of Molecular …, 2024 - Elsevier
The thiazole ring closure of thiosemicarbazones with α-bromo-4-substituted acetophenones
was carried out to generate aminothiazole analogues (A1–A16). Experimental methods …

Cascade and multicomponent synthesis of structurally diverse 2-(pyrazol-3-yl) pyridines and polysubstituted pyrazoles

R Barroso, MP Cabal, A Jiménez… - Organic & Biomolecular …, 2020 - pubs.rsc.org
The cascade reaction between N-tosylhydrazones and 2-alkynylpyridines leads to 2-
(pyrazol-3-yl) pyridines, important structural motifs in ligands for transition metals and …