[HTML][HTML] Orodispersible polymer films with the poorly water-soluble drug, olanzapine: hot-melt pneumatic extrusion for single-process 3D printing

HW Cho, SH Baek, BJ Lee, HE ** - Pharmaceutics, 2020 - mdpi.com
Amorphous solid dispersions (ASDs) improve the oral delivery of poorly water-soluble
drugs. ASDs of olanzapine (OLZ), which have a high melting point and low solubility, are …

Response surface method for optimization of prepared satranidazole powder layered pellets

R Mazumder, B Mahanti, S Majumdar, R Pal… - Future Journal of …, 2021 - Springer
Background The purpose of the present study was to evaluate layered of satranidazole
powder using natural polysaccharides as coating materials for colon targeting that were …

Formulation and in vitro evaluation of a thermoreversible mucoadhesive nasal gel of itopride hydrochloride

MA Marzouk, DA Osman… - Drug Development and …, 2018 - Taylor & Francis
Itopride hydrochloride (ITO HCl) is a prokinetic agent, used in the treatment of
gastrointestinal motility disorders. The aim of the study was to develop stable mucoadhesive …

Development and characterization of lyophilized cefpodoxime proxetil-Pluronic® F127/polyvinylpyrrolidone K30 solid dispersions with improved dissolution and …

G Yurtdaş-Kırımlıoğlu - Pharmaceutical Development and …, 2021 - Taylor & Francis
The aim of this study was the development of hard-cellulose capsules containing
cefpodoxime proxetil (CEF)(BCS Class II) loaded novel Pluronic® F127 (P127) …

[HTML][HTML] Solubility enhancement study of lumefantrine by formulation of liquisolid compact using mesoporous silica as a novel adsorbent

S Bhattacharyya, D Ramachandran - Materials Letters: X, 2022 - Elsevier
Lumefantrine, exhibits poor bioavailability due to its very low solubility. A liquisolid compact
of lumefantrine was prepared with mesoporous silica as a novel coating material. Lactose …

[PDF][PDF] In vitro dissolution similarity as a surrogate for in vivo bioavailability and therapeutic equivalence

SA Helmy, HM El Bedaiwy - Dissolution Technol, 2016 - dissolutiontech.com
Generic immediate-release solid oral dosage forms containing BCS Class I and III drugs that
have similar in vitro dissolution profiles might receive market authorization without in vivo …

Spray dried nanospheres for inclusion complexes of cefpodoxime proxetil with β-cyclodextrin, 2-hydroxypropyl-β-cyclodextrin and methyl-β-cyclodextrin: improved …

G Yurtdaş-Kırımlıoğlu - Drug Development and Industrial Pharmacy, 2021 - Taylor & Francis
Objective The aim of the current research was the development hard cellulose capsules
containing cefpodoxime proxetil (CEF)(BCS-Class II) encapsulated nanospheres of …

Development and validation of in vitro discriminatory dissolution testing method for fast dispersible tablets of BCS class II drug

S Bhatt, ROY Dabashis, M Kumar… - Turkish Journal of …, 2020 - pmc.ncbi.nlm.nih.gov
Objectives: Fast dispersible tablets (FDTs) get dispersed very fast due to which the
discrimination of in vitro drug release and their evaluation is difficult. Hence in the present …

Characterization of Alternative Starches and Its Effects on the In Vitro Dissolution of Capsules Containing Low Solubility Drugs (Ibuprofen and Nifedipine)

A de Freitas Santos Júnior… - Starch …, 2024 - Wiley Online Library
Biopharmaceutical applications of alternative starches (ASs), as excipients in capsules
containing low solubility drugs (nifedipine and ibuprofen), from seeds of breadfruit …

[HTML][HTML] Evaluation of physicochemical properties and dissolution studies on quality control of low water solubility drugs (raw materials and pharmaceutical …

M da Silva Ferreira… - … de Ciencias Químico …, 2020 - scielo.org.co
The purpose of this study was to evaluate physicochemical properties and dissolution
studies of furosemide (FUR), hydrochlorothiazide (HCTZ) and nifedipine (NIF), low water …