Consideration of pathways for immunotoxicity of per-and polyfluoroalkyl substances (PFAS)

V Ehrlich, W Bil, R Vandebriel, B Granum, M Luijten… - Environmental …, 2023 - Springer
Background Per-and polyfluoroalkyl substances (PFAS) are of public health concern,
because of their ubiquitous and extremely persistent occurrence, and depending on their …

And now for something completely different: diversity in ligand-dependent activation of Ah receptor responses

MS Denison, SC Faber - Current opinion in toxicology, 2017 - Elsevier
Ligand-dependent activation of the Ah receptor (AhR) can result in an extremely diverse
spectrum of biological and toxic effects that occur in a ligand-, species-and tissue-specific …

Dioxin toxicity, aryl hydrocarbon receptor signaling, and apoptosis—Persistent pollutants affect programmed cell death

M Chopra, D Schrenk - Critical reviews in toxicology, 2011 - Taylor & Francis
Exogenous ligands of the aryl hydrocarbon receptor (AhR) such as 2, 3, 7, 8-
tetrachlorodibenzo-p-dioxin (TCDD) and related substances are highly toxic pollutants …

Concentration effect of gold nanoparticles on proliferation of keratinocytes

S Lu, D **a, G Huang, H **g, Y Wang, H Gu - Colloids and Surfaces B …, 2010 - Elsevier
34nm gold nanoparticles with good stability were synthesized and characterized and their
effect (as a function of concentration) on the proliferation of keratinocytes was evaluated by …

[HTML][HTML] Rapid visualization of PD-L1 expression level in glioblastoma immune microenvironment via machine learning cascade-based Raman histopathology

QQ Zhou, J Guo, Z Wang, J Li, M Chen, Q Xu… - Journal of Advanced …, 2024 - Elsevier
Introduction Combination immunotherapy holds promise for improving survival in responsive
glioblastoma (GBM) patients. Programmed death-ligand 1 (PD-L1) expression in immune …

Induction of intracellular calcium concentration by environmental benzo (a) pyrene involves a β2-adrenergic receptor/adenylyl cyclase/Epac-1/inositol 1, 4, 5 …

A Mayati, N Levoin, H Paris, M N'Diaye… - Journal of Biological …, 2012 - jbc.org
Polycyclic aromatic hydrocarbons (PAHs) such as benzo (a) pyrene (B (a) P) are widely
distributed environmental contaminants, known as potent ligands of the aryl hydrocarbon …

Endocrine disruptor, dioxin (TCDD)-induced mitochondrial dysfunction and apoptosis in human trophoblast-like JAR cells

SC Chen, TL Liao, YH Wei, CR Tzeng… - MHR: Basic science of …, 2010 - academic.oup.com
Abstract The endocrine disruptor 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) has been
demonstrated to disrupt hormone signalling, reduce fertility, interfere with embryo …

Trichlorfon-induced apoptosis in hepatocyte primary cultures of Carassius auratus gibelio

WN Xu, WB Liu, ZP Liu - Chemosphere, 2009 - Elsevier
Trichlorfon, an organophosphorus pesticide, can disrupt metabolism, reproduction and
immune functions of some aquatic animals. In the present study, the effect of trichlorfon on …

Association of dioxin and other persistent organic pollutants (POPs) with diabetes: epidemiological evidence and new mechanisms of beta cell dysfunction

V De Tata - International journal of molecular sciences, 2014 - mdpi.com
The worldwide explosion of the rates of diabetes and other metabolic diseases in the last
few decades cannot be fully explained only by changes in the prevalence of classical …

Benzo[a]pyrene Increases the Nrf2 Content by Downregulating the Keap1 Message

PM Nguyen, MS Park, M Chow, JH Chang… - Toxicological …, 2010 - academic.oup.com
We employed the suppressive subtractive hybridization to identify 41 up-and downregulated
transcripts in Jurkat cells after benzo [a] pyrene (BaP) treatment. Among the 21 …