Potential anticancer properties and mechanisms of action of curcumin

NG Vallianou, A Evangelopoulos, N Schizas… - Anticancer …, 2015 - ar.iiarjournals.org
Curcumin, a yellow substance belonging to the polyphenols superfamily, is the active
component of turmeric, a common Indian spice, which is derived from the dried rhizome of …

Potential roles for the kisspeptin/kisspeptin receptor system in implantation and placentation

KL Hu, HM Chang, HC Zhao, Y Yu… - Human reproduction …, 2018 - academic.oup.com
BACKGROUND Initially identified as suppressors of metastasis in various types of cancer,
kisspeptins are a family of neuropeptides that are key regulators of the mammalian …

[HTML][HTML] Dysregulated Sp1/miR-130b-3p/HOXA5 axis contributes to tumor angiogenesis and progression of hepatocellular carcinoma

Y Liao, C Wang, Z Yang, W Liu, Y Yuan, K Li… - Theranostics, 2020 - ncbi.nlm.nih.gov
Angiogenesis, one of the hallmarks of cancer, is essential for both tumor growth and
metastasis. However, its molecular mechanisms in hepatocellular carcinoma (HCC) are …

[PDF][PDF] Role of Rho GTPases and their regulators in cancer progression

R Rathinam, A Berrier, SK Alahari - Front Biosci, 2011 - researchgate.net
[Frontiers in Bioscience 16, 2561-2571, June 1, 2011] Role of Rho GTPases and their regulators
in cancer progression Rajamani R Page 1 [Frontiers in Bioscience 16, 2561-2571, June 1 …

Usnic acid inhibits breast tumor angiogenesis and growth by suppressing VEGFR2-mediated AKT and ERK1/2 signaling pathways

Y Song, F Dai, D Zhai, Y Dong, J Zhang, B Lu, J Luo… - Angiogenesis, 2012 - Springer
Tumor growth depends on angiogenesis and inducing angiogenesis is one of the most
important hallmarks in the cancer development. Treatment with small molecules that inhibit …

Role of neurotrophins in pregnancy and offspring brain development

A Sahay, A Kale, S Joshi - Neuropeptides, 2020 - Elsevier
Neurotrophins are a family of functionally and structurally related proteins which play a key
role in the survival, development, and function of neurons in both the central and peripheral …

Twice‐weekly administration of kisspeptin‐54 for 8 weeks stimulates release of reproductive hormones in women with hypothalamic amenorrhea

CN Jayasena, GMK Nijher, A Abbara… - Clinical …, 2010 - Wiley Online Library
Kisspeptin is a novel therapeutic target for infertility. A single kisspeptin‐54 (KP‐54) injection
acutely stimulates the release of reproductive hormones in women with hypothalamic …

Anticancer and antiangiogenic iron (II) complexes that target thioredoxin reductase to trigger cancer cell apoptosis

L **e, Z Luo, Z Zhao, T Chen - Journal of medicinal chemistry, 2017 - ACS Publications
Thioredoxin reductase (TrxR) is a selenoenzyme that could regulate intracellular oxidative
balance and found to be overexpressed in many human tumor cells. Due to its important role …

Kisspeptin: beyond the brain

M Bhattacharya, AV Babwah - Endocrinology, 2015 - academic.oup.com
The hypothalamic-based kisspeptin-signaling system is a major positive regulator of the
neuroendocrine-reproductive axis in mammals. During the last decade, major advances …

Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-α/VEGF/Rho-GTPases: pivotal role of STAT-3

SR Boreddy, RP Sahu, SK Srivastava - PloS one, 2011 - journals.plos.org
Our previous studies have shown that benzyl isothiocyanate (BITC) suppresses pancreatic
tumor growth by inhibiting STAT-3; however, the exact mechanism of tumor growth …