Mechanical properties of cell sheets and spheroids: the link between single cells and complex tissues

YM Efremov, IM Zurina, VS Presniakova… - Biophysical …, 2021 - Springer
Cell aggregates, including sheets and spheroids, represent a simple yet powerful model
system to study both biochemical and biophysical intercellular interactions. However, it is …

[HTML][HTML] Towards clinical translation of the cell sheet engineering: Technological aspects

IM Zurina, VS Presniakova, DV Butnaru… - Smart Materials in …, 2023 - Elsevier
Cell sheet engineering is a rapidly growing field of tissue engineering and regenerative
medicine. The ease of cell sheet obtainment techniques and the resulting unique …

Micropatterned cell sheets as structural building blocks for biomimetic vascular patches

NG Rim, A Yih, P Hsi, Y Wang, Y Zhang, JY Wong - Biomaterials, 2018 - Elsevier
To successfully develop a functional tissue-engineered vascular patch, recapitulating the
hierarchical structure of vessel is critical to mimic mechanical properties. Here, we use a cell …

Fabrication and Characterization of Recombinant Silk‐Elastin‐Like‐Protein (SELP) Fiber

EG Roberts, NG Rim, W Huang… - Macromolecular …, 2018 - Wiley Online Library
Silk‐elastin‐like‐protein polymers (SELPs) are genetically engineered recombinant protein
sequences consisting of repeating units of silk‐like and elastin‐like blocks. By combining …

A robust method to generate mechanically anisotropic vascular smooth muscle cell sheets for vascular tissue engineering

DE Backman, BL LeSavage, SB Shah… - Macromolecular …, 2017 - Wiley Online Library
In arterial tissue engineering, mimicking native structure and mechanical properties is
essential because compliance mismatch can lead to graft failure and further disease. With …

Generation of a purified iPSC-derived smooth muscle-like population for cell sheet engineering

G Kwong, HA Marquez, C Yang, JY Wong, DN Kotton - Stem Cell Reports, 2019 - cell.com
Induced pluripotent stem cells (iPSCs) provide a potential source for the derivation of
smooth muscle cells (SMCs); however, current approaches are limited by the production of …

Silk-fibronectin protein alloy fibres support cell adhesion and viability as a high strength, matrix fibre analogue

MM Jacobsen, D Li, N Gyune Rim, D Backman… - Scientific Reports, 2017 - nature.com
Silk is a natural polymer with broad utility in biomedical applications because it exhibits
general biocompatibility and high tensile material properties. While mechanical integrity is …

Introducing biomimetic shear and ion gradients to microfluidic spinning improves silk fiber strength

D Li, MM Jacobsen, NG Rim, D Backman… - …, 2017 - iopscience.iop.org
Silkworm silk is an attractive biopolymer for biomedical applications due to its high
mechanical strength and biocompatibility; as a result, there is increasing interest in scalable …

Detection techniques of biological and chemical Hall sensors

H Fan, J Wang, Q Feng, Q Hu, S Zuo, V Nabaei… - RSC …, 2021 - pubs.rsc.org
Integrated magnetic Hall effect sensors have been widely used in people's daily life over the
past decades, and still are gaining enormous attention from researchers to establish novel …

On force and form: Mechano-biochemical regulation of extracellular matrix

GA Hoffmann, JY Wong, ML Smith - Biochemistry, 2019 - ACS Publications
The extracellular matrix is well-known for its structural role in supporting cells and tissues,
and its important biochemical role in providing signals to cells has increasingly become …